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https://www.amazon.com/Controlled-Delivery-McGraw-Hill-Chemical-Engineering/dp/0071417591
A RIGOROUS EXPLORATION OF THE STATE OF THE ART IN CONTROLLED RELEASE DRUG DELIVERY Written by an International team of experts, this comprehensive text offers pharmaceutical scientists and engineers working in the field, state-of-the-art design principles for the development and bioengineering of drug delivery systems/technology.Author: Xiaoling Li, Bhaskara R Jasti
https://www.amazon.com/Controlled-Delivery-McGraw-Hill-Chemical-Engineering-ebook/dp/B000Y2I78G
A RIGOROUS EXPLORATION OF THE STATE OF THE ART IN CONTROLLED RELEASE DRUG DELIVERY Written by an International team of experts, this comprehensive text offers pharmaceutical scientists and engineers working in the field, state-of-the-art design principles for the development and bioengineering of drug delivery systems/technology.Manufacturer: McGraw-Hill Education
https://pdfs.semanticscholar.org/2079/b751e16d7a9d34d2e0604a35a312d5bca4b2.pdf
According to the diffusion principle, controlled-release drug delivery systems can be designed as a reservoir system or a matrix system. Drugs released from both reservoir and matrix type devices follow the principle of diffusion, but they show two different release patterns as shown in Fig.
http://www.thepharmajournal.com/vol1Issue10/Issue_dec_2012/3.1.pdf
of the original controlled-release systems was to achieve a delivery profile that would yield a high blood level of the drug over a long period of time. With traditional drug delivery systems, the drug level in the blood follows the in which the level rises after each administration of the drug and
https://www.mhprofessional.com/9780071417594-usa-design-of-controlled-release-drug-delivery-systems-group
This in-depth text features detailed coverage of: Physiological and biochemical barriers to drug delivery. Pharmacokinetics and pharmacodynamics of drug delivery. Diffusion and dissolution strategies. Prodrugs. Bioadhesive and gastric retentive systems. Physiological and biochemical barriers to …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142099/
Sep 28, 2014 · The controlled drug delivery technology has progressed over the last six decades. It began in 1952 with the introduction of the first sustained release formulation. The 1st generation (1950-1980) of drug delivery was focused on developing oral and transdermal sustained release systems and establishing the controlled drug release mechanisms.Author: Kinam Park
https://www.sciencedirect.com/science/article/pii/B9780128024478000194
Hydrophilic matrix systems are polymer based drug delivery systems designed to control the rate of drug release during the passage of the matrix through the GI tract. 30 During GI transit, the matrices are reduced in size through surface erosion and dissolution, which reduces the probability of expulsion of an exhausted “ghost” tablets usually seen with osmotic pump, hydrophobic matrices or reservoir system. Drug release …Author: Y. Qiu, P.I. Lee
https://www.slideshare.net/suraj_mindgamer/factors-affecting-design-of-controlled-release-drug-delivery-systems
Sep 19, 2014 · Dose Size • Size of the drug plays a major role in determining the size of the final finished product. • In case, the dose already high, then formulating the same into controlled release will further increase the overall dosage size & thereby reduced patient compliance.
https://www.researchgate.net/publication/307671765_ORAL_CONTROLLED_RELEASE_DRUG_DELIVERY_SYSTEM_AN_OVERVIEW
The goal in designing controlled release drug delivery system is to redu ce the fre quency of t he dosing, r educing the dos e and providing uniform dru g delivery. So, controlled release
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