Depofoam Drug Delivery Technology

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DepoFoam Pacira

    http://www.pacira.com/products/depofoam
    Our DepoFoam extended-release drug delivery technology can be applied to both small and large molecules, potentially improving patient care by providing a unique solution for medications that: Need to be administered by continuous infusion or frequent multiple injections

Innovative Technology - Exparel

    https://www.exparel.com/hcp/innovative-technology
    Kohn FR, Malkmus SA, Brownson EA, Rossi SS, Yaksh TL. Fate of the predominant phospholipid component of DepoFoam drug delivery matrix after intrathecal administration of sustained-release encapsulated cytarabine in rats. Drug Deliv. 1998;5(2):143-151. Richard BM, Newton P, Ott LR, et al.

DepoFoam™ technology: a vehicle for controlled delivery of ...

    https://www.sciencedirect.com/science/article/pii/S0168365999001467
    The versatility of DepoFoam drug delivery system as a vehicle for controlled delivery of protein and peptide drugs has been demonstrated. The rate of drug release in these formulations can be modulated to cover a relatively wide range of time courses, from one to two days up to several weeks.Author: Qiang Ye, John Asherman, Mark Stevenson, Elizabeth Brownson, Nandini V Katre

A lipid based depot (DepoFoam® technology) for sustained ...

    https://www.sciencedirect.com/science/article/pii/S0163782702000048
    This article reviews the scientific basis of DepoFoam® technology, a lipid-based drug delivery system. A sustained release depot product (DepoCyt®) utilizing this technology has been clinically developed and recently approved for clinical use by regulatory agencies . DepoFoam formulations of drugs are intended for non-vascular, but parenteral ...Author: Sankaram Mantripragada

DepoFoam(TM) technology: A vehicle for controlled delivery ...

    https://www.researchgate.net/publication/12673157_DepoFoamTM_technology_A_vehicle_for_controlled_delivery_of_protein_and_peptide_drugs
    This challenge has been successfully met in the formulation of several peptide and protein drugs using the DepoFoam, multivesicular lipid-based drug delivery system. DepoFoam technology consists ...

IMPORTANT SAFETY INFORMATION IMPORTANT SAFETY …

    https://www.exparel.com/sites/default/files/PP-EX-US-3647_EXPAREL_Fast_Facts_Update.pdf
    EXPAREL uses DepoFoam®, an innovative drug delivery technology, to extend analgesia. 2 What is the clinical experience with EXPAREL? More than 4.5 million patients have received EXPAREL across a range of soft tissue (eg, abdominal, anorectal, breast, plastic surgery, reconstructive, and genitourinary), oral/maxillofacial,

Pharmacology of Drugs Formulated with DepoFoam™ SpringerLink

    https://link.springer.com/article/10.2165%2F00003088-200645120-00002
    Sep 30, 2012 · Lamellar liposome technology has been used for several decades to produce sustained-release drug formulations for parenteral administration. Multivesicular liposomes are structurally distinct from lamellar liposomes and consist of an aggregation of hundreds of water-filled polyhedral compartments separated by bi-layered lipid septa. The unique architecture of multivesicular liposomes …Author: Martin S. Angst, David R. Drover

DepoDur Uses, Dosage, Side Effects - Drugs.com

    https://www.drugs.com/depodur.html
    DepoDur is a novel single dose sustained-release injectable formulation of morphine providing 48 hours of post-surgical pain relief. About DepoDur. DepoDur is a single dose extended-release injectable formulation of morphine sulphate. DepoDur employs SkyePharma's proprietary DepoFoam technology and is supplied as a ready-to-use suspension.

Pharmacology of drugs formulated with DepoFoam: a ...

    https://www.ncbi.nlm.nih.gov/pubmed/17112293
    Pharmacology of drugs formulated with DepoFoam: a sustained release drug delivery system for parenteral administration using multivesicular liposome technology. Angst MS(1), Drover DR. Author information: (1)Department of Anesthesia, Stanford University School of Medicine, Stanford, CA 94305-5117, USA. [email protected]: Martin S. Angst, David R. Drover

Pacira Pharmaceuticals - Parsippany, NJ - Inc.com

    https://www.inc.com/profile/pacira-pharmaceuticals
    Pacira Pharmaceuticals. Focuses on the development, commercialization, and manufacture of new pharmaceutical products, based on its proprietary DepoFoam drug delivery technology, for use in ...

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