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https://onlinelibrary.wiley.com/doi/full/10.1111/jphp.12104
Jul 19, 2013 · Dendrimers for non‐viral gene delivery Peptide dendrimers. Peptide dendrimers are branched macromolecules consisting... Glycodendrimers. The term ‘glycodendrimer’ is used to describe dendrimers... PEI dendrimers. PEI is another efficient and extensively utilized non‐viral gene carrier... ...Author: Sahil P. Chaplot, Ilva D. Rupenthal
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269116/
3.2. PAMAM dendrimer based targeted gene delivery. Gene therapy requires special methods to deliver nucleic acids into the targeted cells and tissues. This is because nucleic acids have a pronounced negative charge due to the phosphate groups linking the …Author: Fereydoon Abedi-Gaballu, Fereydoon Abedi-Gaballu, Gholamreza Dehghan, Maryam Ghaffari, Maryam Ghaffa...
https://www.creative-biolabs.com/gene-therapy/development-of-dendrimer-as-gene-delivery-system.htm
PAMAM dendrimers are highly branched nanometer-sized polymers with a multifunctionalized peripheral surface, with a high degree of molecular uniformity, monomolecular weight as well as specific size and shape. PAMAM dendrimers are water soluble, biocompatible and …
https://link.springer.com/chapter/10.1007/978-3-7091-1206-9_14
Nov 05, 2012 · Dendrimeric structures have been suggested to be used in gene therapy as potent carriers capable to, sometimes specifically, deliver DNA or RNA into the cells. Dendrimers are able to form complexes with many types of nucleic acids, such …Author: Jaroslav Šebestík, Milan Reiniš, Jan Ježek
https://pdfs.semanticscholar.org/1744/21b2b94e6cb2bb32144c3682a3a7221d663b.pdf
synthetic gene delivery systems (Fig. 2). 2. Dendrimers Since their conception in the late 1970s and early 1980s the unique properties of dendrimers have spawned a whole range of new research areas ranging from drug and gene delivery applications to process …
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