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https://www.sciencedirect.com/science/article/pii/S1359644604032763
Delivery of anticancer drugs by dendrimers and dendritic polymers. In addition to improving drug properties such as solubility and plasma circulation time , polymeric carriers can also facilitate the passive targeting of drugs to solid tumors . This targeting is possible because of the increased permeability of tumor vasculature to macromolecules and because of limited lymphatic drainage.Author: Elizabeth R. Gillies, Jean M.J. Fréchet
https://www.ncbi.nlm.nih.gov/pubmed/15676297
Jan 01, 2005 · Dendrimers and dendritic polymers in drug delivery. Gillies ER(1), Fréchet JM. Author information: (1)Department of Chemistry, University of California, Berkeley, CA 94720-1460, USA.Author: Elizabeth R. Gillies, Jean M.J. Fréchet
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017392/
Apr 18, 2018 · PAMAM dendrimers are one of the most used dendrimers for drug delivery systems [5,6,7]. The dendrimer architecture has three main sites for drug entrapment by using various mechanisms: (i) void spaces (by molecular entrapment); (ii) branching points (by hydrogen bonding); and (iii) outside surface groups by (charge–charge interactions) ( Figure 1 ).Author: Abhay Singh Chauhan
https://www.researchgate.net/publication/8056400_Dendrimers_and_dendritic_polymers_in_drug_delivery
Dendritic polymers, or dendrimers, have likewise been extensively explored over the last several decades for drug delivery purposes (Gillies and Fréchet, 2005; Kesharwani et al., 2017). These...
https://ijpras.com/storage/models/article/XmN2vjANrdsVrjYHbPeq61vZLo7Y6FzWFaJT8r0WqyekhBpX60o7ah1DKgft/dendritic-polymer-for-drug-delivery-applications.pdf
3. Dendrimers in drug delivery Dendrimers are synthetic, highly branched, spherical, mono-disperse macromolecules of nanometer dimensions, prepared by the iterative synthetic methodology. Since the pioneering work of Tomalia et al. and Newkome et al. on dendrimer synthesis in …
https://www.sciencedirect.com/science/article/pii/S092849311733103X
Dendrimers, as a type of artificial polymers with unique structural features, have been extensively explored for their applications in biomedical fields, especially in drug delivery. However, one important concern about the most commonly used dendrimers exists - the nondegradability, which may cause side effects induced by the accumulation of synthetic polymers in cells or tissues.Author: Da Huang, Da Huang, Decheng Wu
http://wwwcourses.sens.buffalo.edu/ce435/Dendrimers/Dendrimers
The "dendritic box" is a fifth generation poly (propylene imine) consisting of 64 functional groups at the periphery. The trapped foreign molecules cannot diffuse out of the box. Only upon prolong heating, the trapped molecules were able to escape. It is possible to use the "dendritic box" as vehicle for drug delivery.
https://www.sigmaaldrich.com/materials-science/material-science-products.html?TablePage=16375655
Applications of dendrimers Applications highlighted in recent literature include drug delivery, gene transfection, catalysis, energy harvesting, photo activity, molecular weight and size determination, rheology modification, and nanoscale science and technology. 1, 2 Dendrimer synthesis
https://onlinelibrary.wiley.com/doi/book/10.1002/0470845821
With contributions from many of the world's leading scientists in the field of dendritic research and development, Dendrimers and Other Dendritic Polymers provides a comprehensive review of this rapidly expanding and exciting new field of polymer science.
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