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https://pubs.rsc.org/en/content/chapter/bk9780854048526-00062/978-0-85404-852-6
From the book: Dendrimers in Medicine and Biotechnology: New Molecular ToolsAuthor: U. Boas, J. B. Christensen, P. M. H. Heegaard
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074873/
May 21, 2014 · Dendrimers have found applications in transdermal drug delivery systems. Generally, in bioactive drugs having hydrophobic moieties in their structure and low water solubility, dendrimers are a good choice in the field of efficient delivery system [ 63 ].Author: Elham Abbasi, Sedigheh Fekri Aval, Abolfazl Akbarzadeh, Morteza Milani, Hamid Tayefi Nasrabadi, Sang...
https://www.sciencedirect.com/topics/chemistry/dendrimer
The application of dendrimers as drug-delivery devices has a great influence on the development of pharmaceutical sciences. Dendrimers and their host–guest properties are one of the most popular issues in the scientific discipline of supramolecular chemistry.
https://www.pharmatutor.org/articles/dendrimers-novel-drug-delivery-overview
Dendrimers are being used as drug delivery systems for various drugs like anticancer drugs (methotrexate), drug for prevention of HIV, enhancing bioavailability of pilocarpine for ocular drug delivery. Dendrimers help in achieving increased bioavailability, sustained, controlled as well as targeted release of drug.
https://pubs.rsc.org/en/content/articlelanding/2014/tb/c4tb00171k#!
Abstract. Due to their nanometric size, dendrimers have been considered as potentially suitable as new vehicles for drug delivery since their infancy. The association of a dendrimer and a drug may occur in different ways, either through covalent or non-covalent interactions. A non-covalent interaction can be the simple encapsulation inside dendrimers...
https://pubs.acs.org/doi/10.1021/acs.biomac.6b01436
PEGylated Dendrimers as Drug Delivery Vehicles for the Photosensitizer Silicon Phthalocyanine Pc 4 for Candidal Infections Melanie A. Hutnick † Sayeeda Ahsanuddin ‡Author: Melanie A. Hutnick, Sayeeda Ahsanuddin, Linna Guan, Minh Lam, Elma D. Baron, Jonathan K. Pokorski
https://www.sciencedirect.com/science/article/pii/S0014305703001009
The application of dendrimers as host–guest devices may also have an impact for drug delivery in pharmaceutical research. The use of dendritic macromolecules as drug containers offers the potential advantages of prolonging the residence time of the drug in the blood circulatory system, protecting the drug from its environment, increasing the stability of the active and tissue targeting.Author: F. Aulenta, W. Hayes, S. Rannard
https://onlinelibrary.wiley.com/doi/abs/10.1002/9783527610419.ntls0071
Sep 15, 2007 · Dendrimers in Drug Delivery Dendrimers are Versatile Nano‐devices for the Delivery of Diverse Classes of Drugs Dendritic Drug Delivery: Encapsulation of Guest Molecules Dendrimers have Internal Cavities that can Host Encapsulated Guest MoleculesAuthor: Srinivasa‐Gopalan Sampathkumar, Kevin J. Yarema
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1949907/
Jul 16, 2007 · The examples of drug delivery systems of the past (prior to the current nanotechnology revolution) are liposomes, polymeric micelles, nanoparticles, dendrimers, and nanocrystals, as mentioned above. The current drug delivery systems include microchips, microneedle-based transdermal therapeutic systems, layer-by-layer assembled systems, and various microparticles …Author: Kinam Park
https://en.wikipedia.org/wiki/Dendrimer
There are three methods for using dendrimers in drug delivery: first, the drug is covalently attached to the periphery of the dendrimer to form dendrimer prodrugs, second the drug is coordinated to the outer functional groups via ionic interactions, or third the dendrimer acts as a unimolecular micelle by encapsulating a pharmaceutical through the formation of a dendrimer-drug supramolecular assembly.
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