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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097927/
Dendrimers for Drug Delivery and Targeting. The precise control over the distribution of drugs is highly valuable to abolish the typical drawbacks of traditional medicine. Thus, a drug delivery system should be designed to attain the site-specific delivery preferentially.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017392/
Apr 18, 2018 · 2.1. Dendrimer-Drug Delivery Strategy. PAMAM dendrimers were first reported by Tomalia in 1985 [3,4].PAMAM dendrimers are one of the most used dendrimers for drug delivery systems [5,6,7].The dendrimer architecture has three main sites for drug entrapment by using various mechanisms: (i) void spaces (by molecular entrapment); (ii) branching points (by hydrogen bonding); …Author: Abhay Singh Chauhan
https://www.sciencedirect.com/science/article/pii/S0079670013000853
The authors concluded that dendrimer based transdermal delivery system of NSAIDs could be explored as an attractive approach for treating various ailments . Overall, dendrimers hold promise in transdermal drug delivery although available reports are inadequate. 8.1.4. Dendrimers in oral drug deliveryAuthor: Prashant Kesharwani, Keerti Jain, Narendra Kumar Jain
https://en.wikipedia.org/wiki/Dendrimer
The encapsulation increases with dendrimer generation and this method may be useful to entrap drugs with a relatively high therapeutic dose. Studies based on this dendritic polymer also open up new avenues of research into the further development of drug-dendrimer complexes specific for a cancer and/or targeted organ system.
https://www.slideshare.net/AnilPethe/dendrimers-in-drug-delivery-107157133
Jul 23, 2018 · Interactions between the dendrimer and drug to trap the drug inside the dendrimer. Such a system can be used to encapsulate drugs and provide controlled delivery. eg: DNA was complexed with PAMAM dendrimers for gene delivery applications, and hydrophobic drugs and dye molecules were incorporated into various dendrimer cores.
https://onlinelibrary.wiley.com/doi/full/10.1002/advs.201700339
Biocompatible G4.5 PAMAM dendrimer was selected as the basis of the system as it was previously conjugated with l ‐Cys to evaluate drug release under γ‐radiation. 34 However, few studies have focused on the use of dendrimer carriers in cancer radiation therapy and to our knowledge this study is the first to use l ‐Cys as a ...Author: Szu Yuan Wu, Hsiao Ying Chou, Chiou Hwa Yuh, Chiou Hwa Yuh, Chiou Hwa Yuh, Shewaye Lakew Mekuria, Yu...
https://www.slideshare.net/VARSHAAWASAR/dendrimers-a-recent-drug-delivery-system
Aug 04, 2014 · Dendrimer is a branched drug delivery system which have higher affinity for drug entrapment. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising.
https://www.sciencedirect.com/science/article/pii/S0169409X13000288
The authors concluded that PHA-dendrimer matrix achieved clinical objective, and is a very useful material for clinical transdermal drug delivery system . Then, taking this into consideration, the same authors studied the mechanism of the enhancement effect of G2.5-and G3-PAMAM dendrimers [89] .Author: Serge Mignani, Saïd El Kazzouli, Mosto Bousmina, Jean-Pierre Majoral
https://www.pharmatutor.org/articles/dendrimers-carrier-for-oral-drug-delivery-system
Dendrimers drug delivery system are therefore increasingly viewed as an advantageous for bioactive like drugs and gene. Although dendrimer drug delivery requires attention to certain manufacturing and biological consideration to be successful.
https://www.mdpi.com/1420-3049/23/4/938/htm
Application of dendrimers as a drug delivery system started in late 1990s. Dendrimers for drug delivery are employed using two approaches: (i) formulation and (ii) nanoconstruct. In the formulation approach, drugs are physically entrapped in a dendrimer using non-covalent interactions, whereas drugs are covalently coupled on dendrimers in the ...Author: Abhay Singh Chauhan
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