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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548250/
Jul 01, 2011 · Delivery system with rupturable coating layer These systems depend on the disintegration of the coating layer for the release of a drug. The pressure necessary for the rupture of the coating can be achieved by effervescent excipients, swelling agents or osmotic pressure.Author: Deepika Jain, Richa Raturi, Vikas Jain, Praveen Bansal, Ranjit Singh
https://www.sciencedirect.com/science/article/pii/S0168365903004085
The capsular pulsatile drug delivery system consists of (i) a core, which is a drug-containing hard gelatin capsule, (ii) a swelling layer, comprising a superdisintegrant and a binder and (iii) an insoluble but water-permeable polymeric coating (Fig.Author: T. Bussemer, A. Dashevsky, R. Bodmeier
https://www.ijpsonline.com/articles/chronomodulated-drug-delivery-system-of-salbutamol-sulphate-for-the-treatment-of-nocturnal-asthma.pdf
The rupturable pulsatile drug delivery system consisted of a core, a drug containing reservoir, inner or intermediate swelling layer and an outer water insoluble but permeable coating. The swelling layer consisted of hydroxypropyl methyl cellulose (HPMC E5) it was chosen because of its swelling nature
http://www.thepharmajournal.com/archives/2012/vol1issue7/PartA/7.7.pdf
consisting of cores coated with two layers of swelling and rupturable coatings was prepared and evaluated as pulsatile drug delivery system. Cores containing Rosuvastatin calcium as modelAuthor: BK Garg, G. Gnanarajan, P. Kothiyal
https://www.tandfonline.com/doi/abs/10.1080/10717540701606574
Jan 21, 2010 · Diclofenac sodium tablets consisting of core coated with two layers of swelling and rupturable coatings were prepared and evaluated as a pulsatile drug delivery system. Cores containing the drug were prepared by direct compression using microcrystalline cellulose and Ludipress as hydrophilic excipients with the ratio of 1:1.Author: Hoda A. El-Maradny
https://www.ijpsonline.com/articles/pulsatile-drug-delivery-systems-an-approach-for-controlled-drug-delivery.pdf
with eroding/soluble or rupturable coating. In multiple-unit systems, however, the pulsatile release is induced by changing membrane permeability or by coating with a rupturable membrane. Single unit pulsatile systems: These are sub-classified as capsule-based systems, osmotic systems, delivery systems with soluble or erodibleAuthor: Shweta Arora, J Ali, Alka Ahuja, Sanjula Baboota, J Qureshi
https://www.sciencedirect.com/science/article/pii/S016836590300508X
A tablet system consisting of cores coated with two layers of swelling and rupturable coatings was prepared and evaluated as pulsatile drug delivery system.Author: Srisagul Sungthongjeen, Srisagul Sungthongjeen, Satit Puttipipatkhachorn, Ornlaksana Paeratakul, And...
https://www.sciencedirect.com/science/article/pii/S0378517311006570
Oct 31, 2011 · Fluidized bed coating was used successfully to coat Type I pellets with swellable and rupturable polymers to give Type II pellets which released the drug after a certain lag time due to rupture of ethylcellulose film. The lag time of the system could be modified by level of swelling layer and rupturable coating.Author: Deepak Yadav, Sachin Survase, Neeraj Kumar
https://www.sciencedirect.com/science/article/pii/S1773224718305446
Ethylcellulose (EC) is a frequently used polymer as rupturable coating of pulsatile delivery system, because of its water insolubility, semi-permeability, adjustable water permeability and mechanical properties . It is a brittle material with sufficient strength to withstand mechanical stress after a …Author: Nattawut Charoenthai, Anuradha Wickramanayaka, Srisagul Sungthongjeen, Satit Puttipipatkhachorn
http://www.rguhs.ac.in/cdc/onlinecdc/uploads/04_P050_7860.doc
Delivery system with rupturable coating layer. Delivery system provided with erodable coating layer. Capsule shaped system provided with release controlling plug.2. A blend of floating and pulsatile principles of drug delivery system would have the advantage that a drug can be released in the upper GI tract after a definite time period of no ...
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