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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2604883/
Dec 10, 2008 · The use of intranasal (IN) administration to target therapeutics to the central nervous system (CNS) has many benefits in the treatment of neurologic disorders. The blood-brain barrier (BBB) restricts the use of numerous therapeutic agents that have been developed to treat memory loss and neurodegeneration because it limits CNS penetration ...Author: Leah R Hanson, William H Frey, William H Frey
https://www.slideshare.net/VARSHAAWASAR/brain-targeted-drug-delivery-system
Aug 04, 2014 · 2. PS Mohanachandran, PG Sindhumol, “Recent trends in brain targeting drug delivery system: An overview”, International Journal of Comprehensive Pharmacy, volume 3, issue 10, page no. 1-9. 3. Drug delivery to the brain, From Wikipedia, the free encyclopedia. 4.
https://www.tandfonline.com/doi/abs/10.3109/1061186X.2015.1068320
Jan 22, 2018 · Moreover, brain distribution studies corroborated the use of C-SLN as a viable vehicle to target drug to brain. Hence, C-SLN was demonstrated to be a promising DTX delivery system to brain as it possessed remarkable biocompatibility, stability and efficacy than other reported delivery systems.Author: Indu Singh, Rajan Swami, Deep Pooja, Manish Kumar Jeengar, Wahid Khan, Ramakrishna Sistla
https://www.sciencedirect.com/book/9780128122181/nanotechnology-based-targeted-drug-delivery-systems-for-brain-tumors
Delivery of chemotherapeutic drugs to brain for treatment of tumor has become a challenging task and attention has been laid to improve the prospects of brain-associated drug delivery. The disrupted vasculature in brain tumor and how novel drug delivery facilitates entry of chemotherapeutic drugs to target site for enhancement of therapeutic ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698461/
Two fundamental difficulties in the delivery of drugs to treat central nervous system (CNS) diseases are the systemic delivery of therapeutics across the bloodbrain-barrier (BBB), and the targeting of drugs to specific tissues or cells within the brain. With the advent and promise of RNA-based therapeutics that utilize RNA interference (RNAi ...Author: Saroj P Mathupala
https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201914751
Jan 29, 2020 · Systemic Brain Delivery of Antisense Oligonucleotides across the Blood–Brain Barrier with a Glucose‐Coated Polymeric Nanocarrier Dr. Hyun Su Min Department of Materials Engineering, Graduate School of Engineering, The University of Tokyo, …Author: Hyun Su Min, Hyun Jin Kim, Mitsuru Naito, Satomi Ogura, Kazuko Toh, Kotaro Hayashi, Beob Soo Kim, Sh...
https://www.nature.com/articles/s41392-017-0004-3
Mar 16, 2018 · Nanocarriers for drug delivery. Nanomedicine is a rapidly developing area that is revolutionizing cancer diagnosis and therapy. Nanoparticles …Author: Sudipta Senapati, Arun Kumar Mahanta, Sunil Kumar, Pralay Maiti
https://www.medlink.com/article/drug_delivery_to_the_central_nervous_system
Overview. The delivery of drugs to the brain is a challenge in the treatment of CNS disorders. The major obstruction to CNS drug delivery is the blood-brain barrier, which limits the access of drugs to the brain substance.This article describes various strategies to facilitate drug …
https://rnanano.osu.edu/Guo/Papers/2015%20-%20Oncotarget%20-%20Lee%20et%20al.%20-%20RNA%20nanoparticle%20as%20a%20vector%20for%20targeted%20siRNA%20delivery%20into%20glioblastoma%20mouse%20model
RNP for systemic delivery of therapeutic RNA, such as siRNA and miRNA, into brain tumors in a mouse model system. For targeted delivery of siRNA into brain tumors, a multifunctional RNP was constructed, as previously described [7, 12, 13, 22], using a scaffold based on pRNA sequences of phi29 bacteriophage with slight
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