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https://www.sciencedirect.com/science/article/pii/S0168365902002821
Furthermore, maize seed is a natural protein storage site that can be harnessed as a powerful vehicle for oral delivery of antigens. The natural bioencapsulation of proteins in maize seed may enhance antigen survival in the gut and promote antigen delivery to mucosal surfaces [11], [13], [18], [19], [20].Author: Barry J Lamphear, Stephen J Streatfield, Joseph M Jilka, Christopher A Brooks, Donna K Barker, Debra...
https://www.researchgate.net/publication/10992897_Delivery_of_subunit_vaccines_in_maize_seed
Delivery of subunit vaccines in maize seed Article in Journal of Controlled Release 85(1-3):169-80 · January 2003 with 35 Reads How we measure 'reads'
https://europepmc.org/abstract/MED/12480322
Jan 01, 2003 · The use of recombinant gene technologies by the vaccine industry has revolutionized the way antigens are generated, and has provided safer, more effective means of protecting animals and humans against bacterial and viral pathogens. Viral and bacterial antigens for recombinant subunit vaccines have been produced in a variety of organisms.Author: Barry J Lamphear, Stephen J Streatfield, Joseph M Jilka, Christopher A Brooks, Donna K Barker, Debra...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445721/
Jun 09, 2015 · A maize-based oral vaccine candidate with all of the above attributes has been developed against HBV using the hepatitis B surface antigen (HBsAg) as the target subunit. This was used to demonstrate the key attributes, above, using the same subunit used in the majority of commercial parenteral HBV vaccines.Author: Celine A. Hayden, Maria E. Fischer, Bryan L. Andrews, Hayley C. Chilton, Debra D. Turner, John H. Wa...
https://www.hindawi.com/journals/jir/2019/8303648/
Intradermal immunization for vaccine delivery is an upcoming strategy showing significant advantages over conventional vaccination routes. In particular, in the last few years, intradermal vaccination has gained momentum as an alternative and more effective vaccine delivery route, both from a scientific and a commercial point of view (Table 3).Author: E. Criscuolo, V. Caputo, V. Caputo, R. A. Diotti, R. A. Diotti, G. A. Sautto, G. A. Kirchenbaum, N. ...
https://www.sciencedirect.com/science/article/pii/S0264410X04002518
Cereal seeds are particularly well-suited systems for the oral delivery of subunit vaccines. They have low water contents and naturally store proteins over long periods of time without degradation.Author: Barry J. Lamphear, Joseph M. Jilka, Lyle Kesl, Mark Welter, John A. Howard, Stephen J. Streatfield
https://www.researchgate.net/scientific-contributions/29145916_Debra_D_Turner
Debra D Turner's 6 research works with 473 citations and 339 reads, including: Oral delivery of wafers made from HBsAg-expressing maize germ induces long-term immunological systemic and mucosal ...
https://www.sciencedirect.com/science/article/pii/S0264410X02006059
Jan 30, 2003 · Corn as a production system for human and animal vaccines. ... The development of subunit vaccines based on antigens produced in plant tissues is an expanding field of research. ... Lamphear BJ, Streatfield SJ, Jilka JM, et al. Delivery of subunit vaccines in maize seed. J Control Release, in press. Google ScholarAuthor: Stephen J Streatfield, Jeffrey R Lane, Christopher A Brooks, Donna K Barker, Miranda L Poage, Jocely...
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