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https://www.amazon.com/Delivery-Protein-Peptide-Drugs-Cancer/dp/1860946275
Written by leading scientists in the field of delivery of protein and peptide drugs to tumors for cancer therapy, this important book provides a broad introduction to the field, with discussion by key experts on the physiological barriers for protein and peptide drugs in tumors, and the different approaches to stabilization of these drugs in biological surroundings, as well as their enhanced ...Author: Vladimir P. Torchilin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539351/
Dec 20, 2012 · This paper discusses the role of peptides in cancer therapy with special emphasis on peptide drugs which are already approved and those in clinical trials. The potential of peptides in cancer treatment is evident from a variety of different strategies that are available to address the progression of tumor growth and propagation of the disease.Author: Jyothi Thundimadathil
https://www.sciencedirect.com/science/article/pii/S0169409X04002686
Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer. ... Transduction occurred across the plasma membrane into breast cancer cells where the peptide bound to XIAP and cIAP1 and displaced caspase 3.Author: Jehangir S. Wadia, Steven F. Dowdy
https://www.ncbi.nlm.nih.gov/pubmed/30428665
Feb 20, 2019 · Recent Advances in Anti-cancer Protein/Peptide Delivery. ... Protein/peptide drugs possess unique advantages, such as high pharmacological potency, molecular specificity, multifunctionality, and low toxicity, and thus hold great potential for use in cancer therapy. In the past decades, great achievements have been made in protein delivery ...Author: Xun Liu, Fan Wu, Yong Ji, Lichen Yin
https://www.sciencedirect.com/science/article/pii/S1740674909000043
Because many protein and peptide drugs have their therapeutic targets inside cells, there is also an important task to bring these drugs into target cells without subjecting them to the lysosomal degradation. This review describes current approaches to the intracellular delivery of protein and peptide drugs.Author: Vladimir Torchilin
https://pubs.acs.org/doi/10.1021/acs.bioconjchem.8b00750
Protein/peptide drugs possess unique advantages, such as high pharmacological potency, molecular specificity, multifunctionality, and low toxicity, and thus hold great potential for use in cancer therapy. In the past decades, great achievements have been made in protein delivery systems, which can protect cargo proteins against detrimental physiological environments and efficiently deliver ...Author: Xun Liu, Fan Wu, Yong Ji, Lichen Yin
https://jhoonline.biomedcentral.com/articles/10.1186/1756-8722-5-70
Nov 09, 2012 · Therapeutic monoclonal antibody (TMA) based therapies for cancer have advanced significantly over the past two decades both in their molecular sophistication and clinical efficacy. Initial development efforts focused mainly on humanizing the antibody protein to overcome problems of immunogenicity and on expanding of the target antigen repertoire.Author: Michael A Firer, Gary Gellerman
https://drug-dev.com/peptide-based-cancer-therapeutics/
Peptides can be used as: direct anti-cancer drugs, cytotoxic drug carriers, vaccines, hormones, radio-nuclide carriers, and drug targets. Though shorter in vivo half-life of peptides is a concern, recent advances in drug delivery systems and peptide modification are expected to override those difficulties. Emergence of Biologics in Cancer Treatment
https://www.researchgate.net/publication/339640822_A_New_NT4_Peptide-Based_Drug_Delivery_System_for_Cancer_Treatment
A New NT4 Peptide-Based Drug Delivery System for Cancer Treatment ... multiple units of chemotherapy drugs to cancer tissue would improve treatment efficacy and greatly advance progress in cancer ...
https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-017-0328-x
Mar 21, 2017 · Evaluation of the use of therapeutic peptides for cancer treatment. ... It has the potential to target the delivery of peptides or drugs to solid tumours . ... The conjugation of XTEN into a protein or peptide resulted in an increase in their half-life [90, 91].Author: Susan Marqus, Elena Pirogova, Terrence J. Piva
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