Delivery Of Oligonucleotides And Analogues

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ChemInform Abstract: Delivery of Oligonucleotides and ...

    https://www.researchgate.net/publication/44699323_ChemInform_Abstract_Delivery_of_Oligonucleotides_and_Analogues_The_Oligonucleotide_Conjugate-Based_Approach
    Targeted delivery can potentially improve the pharmacological effects of antisense and siRNA oligonucleotides. Here, we describe a novel bioconjugation approach to the delivery of splice-shifting ...

Interference of poly(ethylene glycol)-lipid analogues with ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1222774/
    Aug 15, 2002 · In this study, we have studied the effects of PEG-lipid analogues, i.e. PEG coupled to either phosphatidylethanolamine (PE) or ceramide, on cationic-lipid-DNA complex ('lipoplex') assembly and the mechanism of cationic-lipid-mediated delivery of ODNs in vitro.Author: Fuxin Shi, Luc Wasungu, Anita Nomden, Marc C.A. Stuart, Evgeny Polushkin, Jan B.F.N. Engberts, Dick ...

Delivery of oligonucleotides and analogues: the ...

    https://www.ncbi.nlm.nih.gov/pubmed/20575132
    Jul 26, 2010 · Delivery of oligonucleotides and analogues: the oligonucleotide conjugate-based approach. Marlin F(1), Simon P, Saison-Behmoaras T, Giovannangeli C. Author information: (1)Museum National d'Histoire Naturelle, CNRS, UMR7196, Inserm, U565, 43 rue Cuvier, 75005 Paris, France.Author: Fanny Marlin, Philippe Simon, Tula Saison‐Behmoaras, Carine Giovannangeli

Delivery of Oligonucleotides and Analogues: The ...

    https://onlinelibrary.wiley.com/doi/full/10.1002/cbic.201000138
    Jul 19, 2010 · Carrier conjugates: Oligonucleotide‐based therapeutic strategies are moving closer to use in patients, but bench work is still needed. Although oligonucleotides are validated and powerful tools in basic research, their delivery is still the major issue impeding their use as therapeutics.Author: Fanny Marlin, Philippe Simon, Tula Saison‐Behmoaras, Carine Giovannangeli

Peptide-mediated Cell and In Vivo Delivery of Antisense ...

    https://www.cell.com/molecular-therapy-family/nucleic-acids/pdf/S2162-2531(16)30083-X.pdf
    tion.14 Such targeting requires delivery of oligonucleotides in stoichiometric amount to that of the targeted mRNA present in the cell at a given time. Steric blocking also requires the use of strongly binding oligonucleotide analogues to ensure good competition for the mRNA with the proteins involved in transla-tion or other cellular processes.

(PDF) Peptide-mediated cellular delivery of antisense ...

    https://www.researchgate.net/publication/10690760_Peptide-mediated_cellular_delivery_of_antisense_oligonucleotides_and_their_analogues
    Improving the delivery of synthetic oligonucleotides and their analogues into cells is an important goal in the full development of antisense technology for control of gene expression in cell ...

Amazon.com: Oligonucleotides and Analogues: A Practical ...

    https://www.amazon.com/Oligonucleotides-Analogues-Practical-Approach/dp/0199632790
    Oct 18, 2019 · Interest in oligonucleotide synthesis has expanded dramatically since the publication of M. Gait's book in this series in 1984. The process has been automated, new reagents have been developed, and the range of uses for the compounds produced has increased and continues to grow.5/5(1)

Delivery of Oligonucleotides and Analogues: The ...

    https://www.deepdyve.com/lp/wiley/delivery-of-oligonucleotides-and-analogues-the-oligonucleotide-NNNdkoTase
    Jul 26, 2010 · Read "Delivery of Oligonucleotides and Analogues: The Oligonucleotide Conjugate‐Based Approach, ChemBioChem" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.

Oligonucleotide Discovery and Delivery

    https://www.optcongress.com/oligonucleotide
    CHI’s Oligonucleotide Discovery and Delivery conference reveals the latest strategies at the forefront of discovery, chemistry and delivery with in-depth sessions on new chemistries, novel delivery mechanisms and the most important preclinical and clinical advances.

ChemInform Abstract: Delivery of Oligonucleotides and ...

    https://www.deepdyve.com/lp/wiley/cheminform-abstract-delivery-of-oligonucleotides-and-analogues-the-YYWSrJN9Rt
    Nov 23, 2010 · Read "ChemInform Abstract: Delivery of Oligonucleotides and Analogues: The Oligonucleotide Conjugate‐Based Approach, ChemInform" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.

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