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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722627/
Alternative gene therapy . Another means of using bacteria for gene therapy is the so-called Alternative gene therapy (AGT) approach, which is also known as bacterial protein delivery. It is based on the transfer of bacterially expressed therapeutic proteins to the host organism using genetically modified (transformed) bacteria.
https://www.bartleby.com/essay/Gene-Therapy-And-Delivery-Methods-F355ZCDV3RZ3Q
Aug 12, 2016 · Gene Therapy and Delivery Methods: Gene therapy is the method of use of genes by inserting a functioning gene into body cells in order to correct the disease by inactivating altered genes with inserting a genetically modified gene into the body in place of drugs to fight disease (Verma, 1990).
https://seekingalpha.com/article/4305556-gene-therapy-series-2-delivery-systems-in-gene-therapy-including-viral-vectors
Nov 11, 2019 · Examples of gene therapy methods using ex vivo delivery include CAR-T therapies like Yescarta and Kymriah. In vivo delivery: By definition, this means inside the body. In this method…
https://hemophilianewstoday.com/2018/04/02/new-delivery-method-may-improve-targeted-therapies-hemophilia-others-study/
Apr 02, 2018 · A new delivery method using nanospears may open new avenues for safer, faster, and more cost-effective gene therapies for genetic diseases, including hemophilia, a study suggests. A delivery method using nanotubes with a spear-like shape may open new avenues for safer, faster, and more cost-effective gene therapies for several genetic diseases, including hemophilia...
https://www.sciencedirect.com/science/article/pii/S0378517313010351
Theoretically, gene therapy is a simple therapeutic method depending on either replacing a distorted gene by healthy one, or completing a missing gene in order to …Author: D. Ibraheem, A. Elaissari, H. Fessi
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
Jul 06, 2012 · Physical methods of nonviral gene delivery. Physical methods applied for in vitro and in vivo gene delivery are based on making transient penetration in cell membrane by mechanical, electrical, ultrasonic, hydrodynamic, or laser-based energy so that DNA entrance into the targeted cells is facilitated.
https://www.intechopen.com/books/recent-advances-in-novel-drug-carrier-systems/gene-delivery-systems-recent-progress-in-viral-and-non-viral-therapy
Chemical methods use natural and synthetic compounds are to deliver the gene into the cell. The gene delivery system generally includes polymers, liposomes, dendrimers, and cationic lipids. Non-viral vectors have many advantages, such as easy of synthesis, effective targeting of …Author: Erdal Cevher, Ali Demir Sezer, Emre Şefik Çağlar
http://www.biologydiscussion.com/gene/therapy/gene-therapy-ex-vivo-and-in-vivo-gene-therapy-with-diagram/9969
The direct delivery of genes into the cells of a particular tissue is referred to as in vivo gene therapy. The ex vivo gene therapy can be applied to only selected tissues (e.g., bone marrow) whose cells can be cultured in the laboratory. The technique of ex vivo gene therapy involves the following steps (Fig.
http://www.genetherapynet.com/types-of-gene-therapy.html
Types of Gene Therapy. Virtually all cells in the human body contain genes, making them potential targets for gene therapy. However, these cells can be divided into two major categories: somatic cells (most cells of the body) or cells of the germline (eggs or sperm). In theory it is possible to transform either somatic cells or germ cells.
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