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https://www.ncbi.nlm.nih.gov/pubmed/22356721
Scaffold matrices can be used to achieve drug delivery with high loading and efficiency to specific sites. Biomaterials used for fabrication of scaffold may be natural polymers such as alginate, proteins, collagens, gelatin, fibrins, and albumin, or synthetic polymers such as polyvinyl alcohol and polyglycolide.Author: Tarun Garg, Onkar Singh, Saahil Arora, R. S. R. Murthy
https://www.sciencedirect.com/science/article/pii/S0014305719318531
Drug delivery scaffolds are smart alternatives to conventional formulations and allow for controlled spatiotemporal releases of active compounds. In several fields of human health, various methods have emerged with natural and synthetic polymers that make the fabrication of new polymer scaffolds possible.Author: Italo Rodrigo Calori, Gustavo Braga, Priscila da Costa Carvalho de Jesus, Hong Bi, Antonio Claudio T...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716555/
Jul 11, 2013 · Therefore, we explored local delivery of FOLFIRINOX to pancreatic cancer tissue using a drug-eluting scaffold in an orthotopic murine model. Compared with traditional systemic or regional chemotherapy, local drug delivery by a drug-eluting scaffold reduced the dosage required to achieve a comparable anticancer effect by roughly two thirds.Author: Qian Zhan, Baiyong Shen, Xiaxing Deng, Hao Chen, Jiabin Jin, Xing Zhang, Chenghong Peng, Hongwei Li
http://www.ijpsnonline.com/Issues/113.pdf
Vikas V. Gaikwad et al. : Scaffolds for Drug Delivery in Tissue Engineering 113 Scaffolds for Drug Delivery in Tissue Engineering Vikas V. Gaikwad1, Abasaheb B. Patil1, Madhuri V. Gaikwad2* 1S.V.P.M. College of Pharmacy, Malegaon, Baramati Pune - 413102 2Department of Pharmaceutics, R.C. Patel College of Pharmacy, Karvand Naka, Shirpur, Shule - 425405, Maharashtra
https://www.researchgate.net/publication/221853404_Scaffold_A_Novel_Carrier_for_Cell_and_Drug_Delivery
A Novel Carrier for Cell and Drug Delivery 7 through the highly hydrophilic scaffold, mechanical stimulation, or hydrolytic degrada- tion of the scaffold 28 or upon swelling in response to an ...
https://www.sciencedirect.com/science/article/pii/B9780323428620000055
In the following sections applications of nanoparticle- and microparticle-based drug delivery systems in bone regeneration are discussed followed by a brief overview of other recent therapies and their scope. Figure 5.1 shows various forms of drug delivery systems studied for bone regeneration and applied via the scaffold system.Author: Sampada Sawant, Ranjita Shegokar
https://www.pnas.org/content/108/1/67
Jan 04, 2011 · We present a new active porous scaffold that can be remotely controlled by a magnetic field to deliver various biological agents on demand. The active porous scaffold, in the form of a macroporous ferrogel, gives a large deformation and volume change of over 70% under a …Author: David J. Mooney, Xuanhe Zhao
https://journals.sagepub.com/doi/full/10.1177/2280800018817462
Jun 24, 2019 · Recently, many researchers have reported controlled drug delivery using different types of scaffolds. In drug delivery applications, drug uptake is improved by the induction of additional porosity in the alginate gel layer. 2 Moreover, a uniform distribution of this porosity throughout the gel scaffold is essential for optimal function.Author: Jaykumar Bhasarkar, Dharmendra Bal
https://www.pnas.org/content/pnas/108/1/67.full.pdf
Active scaffolds for on-demand drug and cell delivery Xuanhe Zhaoa,b, Jaeyun Kimb, Christine A. Cezarb, Nathaniel Huebschb,c, Kangwon Leeb, ... a new active porous scaffold that can be remotely controlled by a magnetic field to deliver various biological agents on demand.Author: David J. Mooney, Xuanhe Zhao
https://www.researchgate.net/profile/Saahil_Arora/publication/221853404_Scaffold_A_Novel_Carrier_for_Cell_and_Drug_Delivery/links/09e415023a649c2eab000000/Scaffold-A-Novel-Carrier-for-Cell-and-Drug-Delivery.pdf?origin=publication_detail
A Novel Carrier for Cell and Drug Delivery 5 the scaffold should provide a minimal level of biomechanical function that should im-prove progressively until normal tissue function has been restored ...
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