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https://www.researchgate.net/publication/280695461_Advances_in_Respiratory_and_Nasal_Drug_Delivery
Transnasal brain drug targeting could ensure better drug delivery to the brain through the olfactory pathway. Risperidone bioavailability is 66% in extensive metabolizers and 82% in slow metabolizers.
https://www.mdpi.com/journal/pharmaceutics/special_issues/nasal-drug-delivery
Such strategies include novel formulations (micro/nano particles, stent) and delivery devices. Successful respiratory and nasal drug delivery also requires sound experimental methods/model development. This special issue entitled: "Respiratory and Nasal Drug Delivery" will deal with key aspects of modern respiratory and nasal delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146747/
Sep 01, 2010 · Early development of dry powder antipseudomonal antibiotic formulations. Traditional formulation approaches for producing dry powders for inhalation have relied on “top-down” manufacturing methods, where large crystalline drug particles are milled (micronized) to produce fine crystals with a median diameter suitable for inhalation (i.e., 1–5 μm).Author: David E. Geller, Jeffry Weers, Silvia Heuerding
https://www.atsjournals.org/doi/full/10.1513/pats.200409-049TA
Dec 01, 2004 · No noninvasive route of drug delivery provides the bioavailability of the pulmonary epithelium. The lungs are far more permeable to macromolecules than any other portal of entry into the body ().Some of the most promising therapeutic agents are peptides and proteins, which could be inhaled instead of injected, thereby improving compliance.Author: John S. Patton, C. Simone Fishburn, Jeffry G. Weers
https://www.sciencedirect.com/journal/european-journal-of-pharmaceutics-and-biopharmaceutics/vol/44/issue/1
Read the latest articles of European Journal of Pharmaceutics and Biopharmaceutics at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
http://rc.rcjournal.com/content/60/6/941
Jun 01, 2015 · Dr Ari presented a version of this paper at the 53rd R espiratory C are Journal Conference, “Aerosol Drug Delivery in Respiratory Care,” held June 6 and 7, 2014, in St Petersburg, Florida. Dr Ari has disclosed a relationship with Aerogen.Author: Arzu Ari
https://www.sciencedirect.com/science/article/pii/S0954611198902116
IMPROVED DELIVERY OF INHALED STEROIDS 7 imaging demonstrated that BDP was deposited throughout the central, intermediate and peripheral airways with the HFA formulation, while deposition of BDP was largely restricted to the oropharynx and central airways with the CFC product.Author: C.L. Leach
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761861/
Jan 29, 2016 · Background. Intrathecal drug delivery systems can be used to manage refractory or persistent chronic nonmalignant (noncancer) pain. We investigated the benefits, harms, cost-effectiveness, and budget impact of these systems compared with current standards of care for adult patients with chronic pain owing to nonmalignant conditions.
https://www.usa.philips.com/healthcare/education-resources/publications/sleep-and-respiratory-newsletter/articles/on-the-go-with-portable-mesh-nebulizers
The InnoSpire Go portable mesh nebulizer is easy for patients to use, delivers commonly used respiratory meds 8,9 to the lungs quickly for more effective treatment and offers consistent medication delivery. 10,11 It offers a number of advantages compared with jet nebulizers and, for some patient groups, compared with meter dose inhalers and dry powder inhalers.
https://caselaw.findlaw.com/us-supreme-court/529/120.html
FOOD AND DRUG ADMINISTRATION et al. v. BROWN & WILLIAMSON TOBACCO CORP. et al.(2000) No. 98-1152 ... The FDA determined that nicotine is a "drug" and that cigarettes and smokeless tobacco are "drug delivery devices," and therefore it had jurisdiction under the FDCA to regulate tobacco products as customarily marketed--that is, without ...
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