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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061492/
Ophthalmic drug delivery via nanotechnology-based products (<1 μm in diameter) must be further explored, as it fulfills three crucial criteria of ophthalmic drug delivery by enhancing drug permeation, controlled drug release, and selective drug targeting.Author: Henry F. Edelhauser, Cheryl L. Rowe-Rendleman, Michael R. Robinson, Daniel G. Dawson, Gerald J. Chad...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
https://www.healio.com/ophthalmology/cornea-external-disease/news/print/ocular-surgery-news/%7Bd69fee03-15c5-4fbd-a090-4f8a5b294c17%7D/understanding-topical-ophthalmic-drug-delivery-how-much-gets-in
Understanding topical ophthalmic drug delivery: How much gets in? Several obstacles stand in the way of effective ocular drug penetration. Ocular Surgery News U.S. Edition, January 10, 2019 ...
https://www.researchgate.net/profile/Sudip_Das4/publication/279418971_Microparticles_and_Nanoparticles_in_Ocular_Drug_Delivery/links/5b8cd0e3299bf1d5a73a0ba4/Microparticles-and-Nanoparticles-in-Ocular-Drug-Delivery.pdf
ophthalmic drug delivery technique that may enhance dosage form accept-ability while providing sustained release in the ocular milieu (14).
https://www.ondrugdelivery.com/wp-content/uploads/2017/05/1058_GF_ONdrugDelivery_Issue-54_MR.pdf
Ophthalmic Drug Delivery This edition is one in the ONdrugDelivery series of publications from Frederick Furness Publishing. Each issue focuses on a specific topic within the field of drug delivery, and is supported by industry leaders in that field. 12 MONTH EDITORIAL CALENDAR FebPrefilled Syringes MarTransdermal Patches, Microneedles
https://www.drugdelconsulting.com/
Drug Delivery Consulting, Alan L. Weiner, Ph.D. - Expertise in Ophthalmic Drug Delivery Systems, Formulations, Pharmaceutical and Medical Device Development
https://en.wikipedia.org/wiki/Ophthalmic_drug_administration
Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye. These states may include bacterial infections, eye injury, glaucoma, and dry eye. However, there are many challenges associated with topical delivery of drugs to the cornea of the eye.
https://www.ondrugdelivery.com/magazines/ophthalmic-drug-delivery104/
OPTIMISING OPHTHALMIC DRUG DELIVERY FOR THERAPEUTIC EFFECTIVENESS . Barbara Morgan discusses how eye physiology impacts product formulation and choice of dosage form, and how advanced delivery technologies are providing new options for formulators seeking to improve the bioavailability or stability of their ophthalmic treatments.
https://www.mdpi.com/journal/pharmaceutics/special_issues/ophthalmic_drugdelivery
Pharmaceutics, an international, peer-reviewed Open Access journal. Dear Colleagues, Research in ophthalmic drug delivery has developed significant advances in the last years, and efforts have been made to develop more effective topical formulations to increase the …
https://lubrizolcdmo.com/blog/the-fdas-recent-uptick-in-ophthalmic-nda-bla-approvals/
Jun 11, 2019 · Ahead of the webinar, “Overcoming Challenges in Ophthalmic Drug Delivery Including Bioavailability and Sterility,” Ashley Rein, Robert Lee, and Barbara Morgan explored the driving factors behind the recent increase in ophthalmic NDA and BLA approvals. The History of FDA Approvals. For many years it was believed that the golden age of FDA new drug approvals was behind us.
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