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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664963/
Dec 01, 2015 · Biological challenges facing liposomal drug delivery systems. As with any foreign particle that enters the body, liposomes encounter multiple defense systems aimed at recognition, neutralization, and elimination of invading substances. These defenses include the RES, opsonization, and immunogenicity (Willis and Forssen, 1998).Author: Lisa Sercombe, Tejaswi Veerati, Tejaswi Veerati, Fatemeh Moheimani, Sherry Y. Wu, Anil K. Sood, Susa...
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/liposomal-drug-delivery
Liposomal drug delivery systems are very effective in the delivery of vaccines and genes due to their adjuvant property and targeting ability which elicit the immune response of the body through antibody formation and corrected gene inputs. Along with this, the mechanism of vaccine and gene delivery is …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017847/
Apr 14, 2018 · Liposomes as Targeted Drug Delivery System for Cancer Treatment Advancements in liposomal vesicle development have achieved both controlled drug release and targeted drug delivery (disease-specific localisation).Author: Temidayo O. B. Olusanya, Rita Rushdi Haj Ahmad, Daniel M. Ibegbu, James R. Smith, Amal Ali Elkordy
https://www.pharmatutor.org/articles/an-updated-review-on-liposomes-as-drug-delivery-system
Liposomes consist of vesicles composed of bilayers or multilayers that contain or have phospholipids and cholesterol surrounding an aqueous compartment. Drug is entrapped within the liposome and is released from the liposome for absorption at the intestinal membrane surface.Author: Devender Sharma, Aashiya Aara E Ali, Leena R Trivedi
https://www.omicsonline.org/open-access/liposomes-for-drug-delivery-2155-952X276-97370.html
Steps involved in liposome action of drug delivery: 1. Adsorption: Adsorption of liposomes to cell membranes causes its contact on the cell membrane. 2. Endocytosis: Adsorption of liposomes on the cell surface membrane followed by engulfment... 3. Fusion : fusion of lipid bilayers of liposomes ...Author: Durgavati Yadav, Kumar Sandeep, Deepak Pandey, Ranu Kumari Dutta
https://www.naturalmedicinejournal.com/blog/secret-effective-liposomal-delivery
In one study, cellular intake increased 9-fold as the liposome size was decreased from 236 nm to 97 nm, and cellular intake was increased 34-fold at 64 nm. 3 In addition, the therapeutic capabilities of a liposomal delivery system are also related to how fast the body clears the liposomes from the blood.
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