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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293348/
Dec 13, 2011 · Iontophoresis enhances drug delivery across the skin by two principal mechanisms: electrorepulsion and electroosmosis. Electrorepulsion is the direct effect of the applied electric field on a charged permeant. The second mechanism, electroosmosis, results from the fact that the skin supports a net negative charge at physiological pH [42, 43].
https://www.rehabmart.com/category/iontophoresis.htm
Iontophoresis equipment allows medical professionals to administer a non-invasive drug delivery method by applying a mild, non-shocking electrical current through a patch-like electrode which administers medication directly into the skin to help treat hyperhidrosis, or to use for sports injuries by administering anti-inflammatory medications.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852061/
More formally, transdermal iontophoresis should be called electrically assisted transdermal delivery. There are three major enhancing mechanisms for drug flux through the skin, of which iontophoresis (also known as electrorepulsion, or electromigration or the Nernst-Planck effect) is just one.
https://www.sciencedirect.com/science/article/pii/S0169409X03002424
The overview of iontophoretic drug delivery presented here clearly illustrates that a considerable research effort has gone into exploring the feasibility of iontophoresis as a treatment platform for a number of therapeutic areas and many different drug molecules with diverse physicochemical properties.Author: Yogeshvar N. Kalia, Aarti Naik, James Garrison, Richard H. Guy
https://techlinkcenter.org/technologies/iontophoresis-drug-delivery/
Scientists at the VA have recently developed an iontophoresis device for the delivery of drug compositions through the skin. The patented technology is available via patent license agreement to companies that would make, use, or sell it commercially.Phone: (406) 994-7786
https://www.a3bs.com/iontophoresis,pg_916.html
Iontophoresis is a technique using a small electric charge to deliver a medicine or other chemical through the skin. This process is a non-invasive method of propelling high concentrations of a charged substance, normally a medication or bioactive agent, transdermally by repulsive electromotive force using a small electrical charge applied to an io
https://www.alliedacademies.org/articles/iontophoresis-a-functional-approach-for-enhancement-of-transdermal-drug-delivery.pdf
Iontophoresis: A Functional Approach for Enhancement of Transdermal Drug Delivery Prabhakar Panzade*1, Prashant Puranik2 1Shri Bhagwan College of Pharmacy, CIDCO, N-6, Aurangabad - 431003 (MS) India 2 Government College of Pharmacy, Vedant Road, Osmanpura, Aurangabad - 431005 (MS) India ABSTRACTAuthor: Prabhakar Satwaji Panzade
https://www.sciencedirect.com/topics/neuroscience/iontophoresis
Iontophoresis and electroporation are both methods of electrically assisted transdermal drug delivery. Figure 12.5 shows drug penetration pathway in low-voltage iontophoresis and high-voltage electroporation. Iontophoresis is more usually used to deliver hydrophobic low-molecular-weight drugs, whereas electroporation appears more effective for the delivery of some macromolecules such as ...
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