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https://www.ncbi.nlm.nih.gov/pubmed/28752598
Next, we aim to give a brief overview, which provides an emphasis and discussion of recent reports using supercritical carbon dioxide (SC-CO2 ) for fabrication of polymeric carriers, for applications in areas related to drug delivery, tissue engineering, bio-imaging, and other biomedical applications. We finally summarize with perspectives.Author: Ranjith Kumar Kankala, Yu Shrike Zhang, Shi-Bin Wang, Chia-Hung Lee, Ai-Zheng Chen
https://www.sciencedirect.com/journal/advanced-drug-delivery-reviews/vol/60/issue/3
Drug Delivery Applications of Supercritical Fluid Technology. Edited by Y. Kawashima, P. York. Volume 60, Issue 3, ... Drug delivery applications of supercritical fluid technology. Yoshiaki Kawashima, Peter York. Pages 297-298 ... select article Biodegradable particle formation for drug and gene delivery using supercritical fluid and dense gas ...
https://onlinelibrary.wiley.com/doi/full/10.1002/adhm.201700433
The supercritical fluid (SCF) technology is perhaps one of the most renowned high‐pressure techniques so far to obtain products with better performances. ... Drug delivery relies on various formulations and strategies for transporting pharmaceutically active compounds to achieve desired therapeutic effects. 4 However, it has been associated ...Author: Ranjith Kumar Kankala, Yu Shrike Zhang, Shi-Bin Wang, Chia-Hung Lee, Ai-Zheng Chen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849475/
[3,6,16c,17] In general, CO 2 is the most used supercritical solvent and is recognized as safe by the United States Food and Drug Administration (US-FDA) in the pharmaceutical processing, i.e., drug delivery applications, because of its low toxicity, low cohesive energy, as well as low density.
http://www.appliedseparations.com/pharmaceuticals.html
In addition, many drug delivery applications provide increased. benefits compared with conventional techniques. Supercritical CO 2 is the most widely used supercritical fluid in the pharmaceutical industry because it has a low critical temperature (31°C), is non-flammable, non-toxic, inexpensive and is Generally Recognized as Safe (GRAS).
http://www.ijnnonline.net/article_38327_32e789112e86cb79465a3d5d307fbb16.pdf
and inexpensive solvent which has been used for preparation of nanodrugs and nanocarriers in drug delivery system with supercritical fluid technology. Delivery of a drug is one of the most challenging research areas in pharmaceutical sciences. With a combination of drugs and innovative delivery systems
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/supercritical-fluid-technology
Apr 03, 2011 · Jiuhong Zhang, ... Jian Zhong, in Nanostructures for Drug Delivery, 2017. 2.4.1 Supercritical fluid technology. Supercritical fluid technology is commonly utilized to prepared nanoparticles from drug solutions. The various methods including the supercritical solution process (RESS), the supercritical antisolvent process and precipitation with compressed antisolvent process …
https://www.researchgate.net/publication/5793189_Drug_delivery_applications_of_supercritical_fluid_technology_Preface
This review summarizes the applications of supercritical fluid transport technology in preparation of controlled-release drug delivery system in recent years and pays more attention on the method ...
https://www.researchgate.net/publication/229095413_Drug_delivery_goes_supercritical
Many review and research articles have been published on the topic of using supercritical fluid techniques for the development of drug delivery [1] [2][3][4][5][6][7], biomedical and ...
https://pdfs.semanticscholar.org/a5c8/1d1eb1c18ebc8f1b7d2cb1bd7a482893dc2b.pdf
The supercritical fluid impregnation proved to be feasible for the preparation of a new ophthalmic drug delivery system26. 3.1.Particle generation and co-precipitation The various stages of particle formation by supercritical fluid processing can be broadly classified into …
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