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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Today, there are 19 transdermal delivery systems for such drugs as estradiol, fentanyl, lidocaine and testosterone; combination patches containing more than one drug for contraception and hormone replacement; and iontophoretic and ultrasonic delivery systems for analgesia ( Table 1, Fig. 1 ).Author: Mark R Prausnitz, Robert Langer
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/dermal-drug-delivery
Dermal drug delivery refers to the targeting of drugs to pathological lesions in the skin while providing minimum systemic absorption. For the treatment of skin diseases such as psoriasis, dermatitis, eczema, skin cancer, and microbial infections, the localization of drug …
https://www.sciencedirect.com/topics/nursing-and-health-professions/transdermal-drug-delivery-system
The transdermal drug delivery system is a technique that provides drug absorption via the skin. The system has many advantages over conventional administration routes such as intravenous or oral administration for systemic and local drug delivery with simple administration.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695828/
Oct 22, 2015 · When drug reaches the dermal layer, it becomes available for systemic absorption via the dermal microcirculation [8,9]. TDD has many advantages over other conventional routes of drug delivery [10,11,12]. It can provide a non-invasive alternative to parenteral routes, thus circumventing issues such as needle phobia .Author: Ahlam Zaid Alkilani, Maelíosa T.C. McCrudden, Ryan F. Donnelly
https://www.crcpress.com/Dermal-Drug-Delivery-From-Innovation-to-Production/Ghosh/p/book/9781466582705
Dermal Drug Delivery: From Innovation to Production - CRC Press Book With the continued advancement of better-quality control and patient outcome reporting systems, changes in the development, control, and regulation of all pharmaceutical delivery systems including transdermal and topical products have been happening on a continuous basis.
http://sustainable-nano.com/2016/09/21/dermal-drug-delivery/
Sep 21, 2016 · The direct application of drugs to the skin and their movement through the skin is called dermal drug delivery. 1-4 Sunscreens, muscle rubs, acne and dermatitis creams are all examples of dermal drug systems, though some (like muscle rubs) are made to penetrate below the skin and others...
https://www.semanticscholar.org/paper/Microneedles%3A-an-approach-in-transdermal-drug-a-Sharma/97bfeee70eb9695a25d92e2108aa7bb6a01cd71a
Delivery of drugs via transdermal route has proved to be the convenient route for various clinical implications. The objective of the present review is to focus on newly innovations in transdermal drug delivery systems which can create a platform for the research and development of pharmaceutical drug dosage form for efficient transdermal delivery.
https://www.researchgate.net/publication/276837593_The_Structure_of_Skin_and_Transdermal_Drug_Delivery_System-A_Review
Transdermal drug delivery system (TDDS) provides a means to sustain drug release as well as reduce the intensity of action and thus reduce the side effects associated with its oral therapy.
https://ijpsr.com/bft-article/transdermal-drug-delivery-system-a-review/?view=fulltext
An advantage of a transdermal drug delivery route over other types of medication delivery such as oral, topical, intravenous, intramuscular, etc. is that the patch provides a controlled release of the medication into the patient, usually through either a porous membrane covering a reservoir of medication or through body heat melting thin layers of medication embedded in the adhesive.
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