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https://medical-dictionary.thefreedictionary.com/transdermal+drug+delivery
Transdermal drug delivery has some benefits: skipping first pass metabolism in liver, steady infusion of a drug over an extended period of time, better compliance of the patient due to ease of usage and reduced frequency of use, a choice for drugs with low therapeutic index and short half life, and so easy elimination of drug when toxicity occurs during the application [3,5,6].
https://www.thefreedictionary.com/Transdermal+Drug+Delivery
Transdermal drug delivery (TDD) has a great advantage over oral administration, which avoids digestion and absorption of the gastrointestinal tract and thus largely reduces drug toxicity and bypasses the first effect of drug absorption, effectively improve the local drug concentration.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs.Author: Mark R Prausnitz, Robert Langer
https://medical-dictionary.thefreedictionary.com/Transdermal+Drug+Delivery+System
across the skin, particularly with reference to the absorption of drugs applied topically for systemic effect. transdermal patch. a drug-impregnated adhesive patch applied to the skin for controlled release of the active compound.
https://www.thefreedictionary.com/Transdermal+Drug+Delivery+System
transdermal patch - a medicated adhesive pad placed on the skin for absorption of a time released dose of medication into the bloodstream. skin patch. estradiol patch - a transdermal patch that allows estradiol to be absorbed into the blood stream; used in treating estrogen deficiency and in hormone replacement therapy.
https://www.merriam-webster.com/dictionary/transdermal
Definition of transdermal. : relating to, being, or supplying a medication in a form for absorption through the skin into the bloodstream transdermal drug delivery transdermal nitroglycerin transdermal nicotine …
https://www.fda.gov/industry/generic-drug-user-fee-amendments/fys-2013-2017-gdufa-science-and-research-report-transdermal-drug-products
Transdermal drug products are administered to the skin, through which the drugs permeate into the systemic circulation and are delivered throughout the body to the site of action. Transdermal products are most frequently developed as transdermal delivery systems (TDS), also known as patches.
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