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https://pubs.acs.org/doi/10.1021/bc0001084
Linear cationic β-cyclodextrin-based polymers (βCDPs) are capable of forming polyplexes with nucleic acids and transfecting cultured cells. The βCDPs are synthesized by the condensation of a diamino-cyclodextrin monomer A with a diimidate comonomer B. In this paper, the effects of polymer structure on polyplex formation, in vitro transfection efficiency and toxicity are elucidated. By ...Author: Suzie J. Hwang, Nathalie C. Bellocq, Mark E. Davis
https://www.researchgate.net/publication/251251429_Cyclodextrin-Containing_Polymers_for_Gene_Delivery
Among them, numerous cyclodextrin-containing polymers gained notable interest [45]. A common property of all cyclodextrin-containing polymers for nucleic-acid delivery is that they are polycations
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307009/
Feb 02, 2012 · The development of linear cyclodextrin-containing polymers (CDPs) for nucleic acid delivery traces back to the mid-1990s in the laboratory of Dr. Mark Davis at Caltech (Figure 3).Author: Jeremy D. Heidel, Thomas Schluep
https://www.researchgate.net/publication/300350240_Cyclodextrin-Containing_Polymers_for_Gene_Delivery
The paper summarizes the history of the drug/gene delivery domain, pointing on polymers as a solution to specific challenges, and outlines the current situation in the field - focusing on the ...
https://link.springer.com/article/10.1023/A:1023063117423
Dec 01, 2002 · Cyclodextrin-containing polymers are now being explored as vehicles for delivering nucleic acids into cells. The structures of the cyclodextrin-containing polycations affect the nucleic acid delivery efficiencies and their toxicities. Of interest is the fact that the cyclodextrin-containing polymers reveal lower toxicities than polymers that lack the cyclodextrins. The cyclodextrins endow the ...Author: Mark E. Davis, Nathalie C. Bellocq
https://www.mdpi.com/journal/polymers/special_issues/cd_containing_polymers
The aim of this Special Issue of Polymers focuses on the current state-of-the-art of cyclodextrin-containing polymers, covering several aspects, such as synthetic routes, structural and dynamic characterization using spectroscopic methods, transport properties of encapsulated substrates, molecular structure and morphology, rheology, and studies ...
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