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http://www.jocpr.com/articles/current-status-of-chronotherapeutic-drug-delivery-system-an-overview.pdf
Current status of chronotherapeutic drug delivery system: An overview Devdhawala Mehul G.* and Seth Avinash K. Department of Pharmacy, Sumandeep Vidyapeeth, Waghodia, Vadodara, …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065827/
Jul 31, 2010 · 3. Hurdles in chonopharmaceutical drug research and development. The current hurdles in chronopharmaceutical drug development include advances in (i) rhythmic biomaterials and system design, (ii) rhythm engineering and modeling (iii) regulatory guidance related to these types of modified dosage forms.Author: Bi-Botti C. Youan
https://en.wikipedia.org/wiki/Chronotherapy_(treatment_scheduling)
For more guidance, see Wikipedia:Translation. Chronotherapy, also called chronotherapeutics or chronotherapeutic drug delivery, refers to the use of circadian or other rhythmic cycles of a condition's symptoms and/or of the individual being treated in the application of therapy.
https://www.researchgate.net/publication/51561273_Chronotherapeutic_Drug_Delivery_Systems_-_An_Approach_to_Circadian_Rhythms_Diseases
The purpose of writing this review on chronotherapeutic drug delivery systems (ChrDDs) is to review the literatures with special focus on ChrDDs and the various dosage forms, techniques that are used to target the circadian rhythms (CR) of various diseases. Many functions of the human body vary considerably in a day.
https://www.slideshare.net/grakbph040/current-status-on-pulsatile-drug-delivery-systems-an-overview
Jun 19, 2018 · Delivery systems with rupturable coating layer and erodible coating layers CONCLUSION Pulsatile drug delivery system will certainly improve patient outcome and optimize disease management in the future.Research in Pulsatile drug delivery system has demonstrated the importance of biological rhythms in drug therapy and this has led to a new approach to the development of drug delivery systems.
http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1567-2018&volume=7&issue=5&spage=370
Aug 06, 2010 · The ultimate goal of current chronopharmaceutical research strives to design ideal chronotherapeutic drug delivery systems that respond to such therapeutic needs. Considering the fact that physiological events such as heart rate, blood pressure, plasma concentration of hormones, plasma proteins and enzymes display constancy over time, drug delivery systems with constant release …
https://benthamscience.com/journals/current-drug-delivery/
Current Drug Delivery aims to publish peer-reviewed articles, research articles, in-depth reviews/mini-reviews, and drug clinical trials studies in the rapidly developing field of drug delivery. Modern drug research aims to build delivery properties of a drug at the design phase, however in many cases this idea cannot be met and the development of delivery systems becomes as important as the development of the drugs …
http://www.jocpr.com/articles/innovations-in-sustained-release-drug-delivery-system-and-its-market-opportunities.pdf
drug delivery system is generally not necessary in such cases. Ideally, the drug should have half-life of three to four hours. b) High therapeutic index: Drugs with low therapeutic index are unsuitable for incorporation in sustained release formulations. If the system fails in the body, dose dumping may occur, leading to fatalities eg.Author: K. P. Sampath Kumar, Debjit Bhowmik, Chiranjib, Margret Ch, ira, K. K.Tripath
https://symbiosisonlinepublishing.com/pharmacovigilance/pharmacovigilance04.php
The main goal of Drug Delivery Research is to develop formulations in order to meet the therapeutic needs for particular pathological conditions. The importance of Biological Rhythms in chronotherapy has been demonstrated in the research of Chronopharmacological field and this brought a new approach to development of Drug Delivery System [5].Author: Musfeera Adeel, Sana Begum, Shaik Gouse, Shanti Kumar
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