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https://www.ncbi.nlm.nih.gov/pubmed/6409505
Critical level of oxygen delivery in anesthetized man. Shibutani K, Komatsu T, Kubal K, Sanchala V, Kumar V, Bizzarri DV. Fifty-eight patients studied were anesthetized with diazepam, pancuronium, and a moderate dose of fentanyl; 99 sets of multiple hemodynamic variables were measured after sternotomy and before cardiopulmonary bypass.Author: Kinichi Shibutani, Toru Komatsu, Keshav Kubal, Vajubhai Sanchala, Vijaya Kumar, Dante V. Bizzarri
http://journals.lww.com/ccmjournal/Abstract/1983/08000/Critical_level_of_oxygen_delivery_in_anesthetized.10.aspx
The relationship between oxygen consumption (Vo 2) and oxygen delivery (Do 2) was studied. The critical value of D02 was identified to be 330 ml/min·M 2 or 8.2 …
https://anesthesiology.pubs.asahq.org/article.aspx?articleid=1945999
A value for critical DO 2 of approximately 5 ml O 2 · kg −1 · min −1 was found in an elderly, anesthetized man, with neuromuscular blockade and mechanically ventilated lungs. 6 However, systematic prospective efforts to determine the critical DO 2 in humans have not been successful.Author: Jeremy A. Lieberman, Richard B. Weiskopf, Scott D. Kelley, John Feiner, Mariam Noorani, Jacqueline L...
https://journal.chestnet.org/article/S0012-3692(15)41173-0/fulltext
Our critical level of O 2 D of 8 ml/min/kg is low by comparison with the data of Danek et al 5 x 5 Danek, SJ, Lynch, JP, Weg, JG, and Dantzker, DR. The dependence of oxygen uptake on oxygen delivery in the adult respiratory distress syndrome. Am Rev Respir Dis. 1980; 122: 387–950Author: Mitchell C. Rashkin, Carol Bosken, Robert P Baughman
https://www.uptodate.com/contents/oxygen-delivery-and-consumption#!
Most of the oxygen binds to hemoglobin in red blood cells, although a small amount dissolves into the plasma. The oxygen is then transported from the lungs to the peripheral tissues, where it is removed from the blood and used to fuel aerobic cellular metabolism.
https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0225541
Previous research specified certain critical oxygen delivery levels associated with acute kidney injury. However, a single universal critical oxygen delivery value is not sensible, as oxygen consumption has to be considered when determining critical delivery values.Author: Rik H. J. Hendrix, Yuri M. Ganushchak, Patrick W. Weerwind, Patrick W. Weerwind
https://link.springer.com/article/10.1007/BF00265110
In healthy tissues, decreases in oxygen delivery (QO n ) do not lower oxygen consumption (VO 2 ) because tissue O 2 extraction increases proportionately. When delivery is reduced below a critical threshold, VO 2 falls because tissue extraction exceeds a critical threshold, and cannot compensate for the reduction in delivery.Author: P. T. Schumacker, S. M. Cain
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874338/
Nov 22, 2019 · Mean oxygen consumption was 56 ± 8 ml/min/m 2, mean oxygen delivery was 281 ± 39 ml/min/m 2. Twenty-seven patients (42%) had an oxygen delivery lower than the previously mentioned critical value of 272 ml/min/m 2. None of the patients developed acute kidney injury according to …Author: Rik H. J. Hendrix, Yuri M. Ganushchak, Patrick W. Weerwind, Patrick W. Weerwind
https://www.sciencedirect.com/science/article/pii/0883944188901098
When oxygen delivery (QO 2 = Qt × CaO 2 ) is reduced in healthy animals, oxygen uptake by tissues (VO 2 ) is maintained by an increase in the O 2 extraction ratio ((CaO 2 − CvO 2 )/CaO 2 ) until a critical level of delivery QO 2C is reached, below which VO 2 becomes dependent on QO 2.Author: G.Richard Long, David P. Nelson, J.Lasha Sznajder, Lawrence D.H. Wood, Paul T. Schumacker
https://acutecaretesting.org/en/articles/increased-blood-lactate-levels-a-marker-of
In addition, a given level of oxygen delivery or oxygen consumption also cannot predict the presence of oxygen supply dependency or increased blood lactate levels [32]. This underlines the importance of measuring lactate levels rather than estimating them from other (biochemical) variables.
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