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https://journals.lww.com/acsm-essr/Pages/articleviewer.aspx?year=2012&issue=01000&article=00007&type=Fulltext
During exercise, coronary blood flow increases to match the augmented myocardial oxygen demand because of tachycardia. Coronary vasodilation during exercise is via a combination of feedforward and feedback control mechanisms. Feedforward control is mediated by sympathetic β …
https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.0954-6820.1971.tb07462.x
The increase in myocardial oxygen demand was thus met almost exclusively by an increase in coronary flow. The myocardial oxygen uptake increased fourfold from rest to heavy exercise with a parallel fourfold increase in the BP 8 × HR product, with a linear relationship over the whole range of values, suggesting that this product is a good index of myocardial oxygen uptake.Author: Stig Holmberg, Wieslaw Serzysko, Edvardas Varnauskas
https://journals.physiology.org/doi/full/10.1152/physrev.00045.2006
The approximately sixfold increase in oxygen demands of the left ventricle during heavy exercise is met principally by augmenting coronary blood flow (∼5-fold), as hemoglobin concentration and oxygen extraction (which is already 70–80% at rest) increase only modestly in most species.Author: Dirk J. Duncker, Robert J. Bache
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC459166/
Oxygen extraction rate of the myocardium at rest and on exercise in various conditions.Author: K Binak, N Harmanci, N Sirmaci, N Ataman, H Ogan
https://www.researchgate.net/publication/11313776_Coronary_blood_flow_control_is_impaired_at_rest_and_during_exercise_in_conscious_diabetic_dogs
Coronary venous PO2 decreased from 19.4+/-0.6 mmHg at rest to 14.7+/-0.7 mmHg during exercise. Diabetes significantly attenuated exercise coronary hyperemia and reduced coronary venous PO2 at rest...
http://www.cvphysiology.com/CAD/CAD002
Oxygen is supplied to the heart muscle (myocardium) by the coronary circulation. Coronary blood flow is determined by hemodynamic factors such as perfusion pressure and vascular resistance. The latter is determined by vascular anatomy and structure, as well as by changes in diameter of the vascular lumen resulting from contraction and relaxation of vascular smooth muscle ( local regulation of blood flow ).
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