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http://www.thepharmajournal.com/vol1Issue10/Issue_dec_2012/3.1.pdf
of the original controlled-release systems was to achieve a delivery profile that would yield a high blood level of the drug over a long period of time. With traditional drug delivery systems, the drug level in the blood follows the in which the level rises after each administration of the drug and
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142099/
Sep 28, 2014 · The controlled drug delivery technology has progressed over the last six decades. It began in 1952 with the introduction of the first sustained release formulation. The 1st generation (1950-1980) of drug delivery was focused on developing oral and transdermal sustained release systems and establishing the controlled drug release mechanisms.Author: Kinam Park
https://www.medindia.net/patients/patientinfo/drug-delivery-system.htm
Drug delivery systems, is a technology using various chemicals to bind the target drugs, carry them to target organ, tissue or cell where the drug is released at a pre-determined rate.
https://www.sciencedirect.com/science/article/pii/S0168365914002508
Controlled drug delivery technology has progressed over the last six decades. This progression began in 1952 with the introduction of the first sustained release formulation. The 1st generation of drug delivery (1950–1980) focused on developing oral and transdermal sustained release systems and establishing controlled drug release mechanisms.Author: Kinam Park
https://www.researchgate.net/publication/307671765_ORAL_CONTROLLED_RELEASE_DRUG_DELIVERY_SYSTEM_AN_OVERVIEW
The aim of oral controlled release drug delivery system is to achieve better bioavailability and release the drug from the system to the target site, which should be predictable and reproducible ...
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/controlled-drug-release
Polymers applied to controlled drug release are often referred to as treatment polymers. The main purpose of the application of polymers for drug delivery systems is in controlled drug release. In these usages, drugs are trapped or mixed in polymer matrices (Vilar et al., 2012).
https://www.journals.elsevier.com/journal-of-controlled-release/
The Journal of Controlled Release (JCR) publishes high-quality research articles in the broad field of delivery science and technology. This includes drug delivery systems and all aspects of formulations, such as physicochemical and biological properties of drugs, design and characterization of dosage...
https://www.slideshare.net/ganapati123/controlled-drug-delivery-systems
Mar 18, 2013 · CONTROLLED DRUG DELIVERY SYSTEMS 1. 1 2. Controlled release• To achieve prolong therapeutic effect.• Implies predictability in drug release kinetics.• Deliver the drug at pre determined rate, locally or systematically. 2 3. Advantages• Improve patient convenience.• Reduction in fluctuation in steady state level.•
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719420/
Poly-lactic-co-glycolic acid (PLGA) has been the most successful polymeric biomaterial for use in controlled drug delivery systems. There are several different chemical and physical properties of PLGA that impact the release behavior of drugs from PLGA delivery devices.Author: Daniel J. Hines, David L. Kaplan
http://www.bioline.org.br/pdf?pr08028
multiparticulate drug delivery systems are especially suitable for achieving controlled or delayed release oral formulations with low risk of dose dumping, flexibility of blending to attain different release patterns as well as reproducible and short gastric residence time. The release of drug from microparticles
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