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https://www.sciencedirect.com/science/article/pii/S0022354915501986
Advances in the understanding of the pathogenesis of infectious diseases and cancer immunology have inspired many new approaches to vaccine developmen…Author: Z. Zhao, K.W. Leong
https://www.ncbi.nlm.nih.gov/pubmed/8961136
1. J Pharm Sci. 1996 Dec;85(12):1261-70. Controlled delivery of antigens and adjuvants in vaccine development. Zhao Z(1), Leong KW. Author information: (1)Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA. Advances in the understanding of the pathogenesis of infectious diseases and cancer immunology have inspired many …Author: Z. Zhao, K.W. Leong
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1123275/
Jun 01, 2002 · Vaccines are hailed as one of the most important public health achievements of the 20th century. 1 In the next five to 15 years, new vaccines and new vaccine delivery technology will fundamentally change how clinicians prevent and treat disease, with a substantial impact on public health. This review describes recent developments in the basic science underpinning the development …Author: Gregory A. Poland, Dennis L Murray, Ruben Bonilla-Guerrero
https://www.sciencedirect.com/science/article/pii/S0168365918300452
Considering the important role of temporal control over vaccine delivery in different diseases [23,31], an Ace-DEX delivery platform with tunable degradation profiles may provide the opportunity to achieve controlled adjuvant or antigen delivery and tunable immune activation, contributing to optimal immune responses and the development of safer ...Author: Naihan Chen, Monica M. Johnson, Michael A. Collier, Matthew D. Gallovic, Eric Bachelder, Kristy Mari...
https://www.researchgate.net/publication/236661087_Mesoporous_silica_nanoparticles_as_antigen_carriers_and_adjuvants_for_vaccine_delivery
Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery. ... Development of an efficient vaccine formulation requires careful selection of a potent antigen ...
https://www.immunology.org/public-information/bitesized-immunology/vaccines-and-therapeutics/adjuvants-particulate-antigen
Adjuvants: particulate antigen delivery systems. Download A.ppt (561.5 KB) Download Adjuvants ... The majority of formulations in development are based on naturally occurring phosphatidylcholine. ... has a good safety profile in humans as they have been used for sutures and controlled drug delivery therapeutics for many years.
https://www.bmj.com/content/324/7349/1315
Jun 01, 2002 · Vaccines are hailed as one of the most important public health achievements of the 20th century.1 In the next five to 15 years, new vaccines and new vaccine delivery technology will fundamentally change how clinicians prevent and treat disease, with a substantial impact on public health. This review describes recent developments in the basic science underpinning the development …Author: Gregory A. Poland, Dennis L Murray, Ruben Bonilla-Guerrero
https://www.creative-biolabs.com/vaccine/delivery-system-optimization.htm
Creative Biolabs has experts in formulation development. Our vaccines delivery optimization strategies can provide you with the best advice and accelerate your vaccine development program. Delivery System At present, there are many diseases for which the development of an effective vaccine is …
https://www.researchgate.net/publication/257740125_Vaccine_antigens
Recombinant/DNA approaches to vaccine antigens. Protein antigens are produced using recombinant DNA technology, where the DNA sequence coding for the antigenic protein is inserted into an ...
http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1003001
We introduce recent developments towards specifically tailored antigens, adjuvants, and delivery systems, and discuss the methodological gaps and lack of knowledge still hampering true rational vaccine design. Finally, we address the potential and limitations of different strategies and technologies for advancing vaccine development.
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