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http://www.thepharmajournal.com/vol1Issue10/Issue_dec_2012/3.1.pdf
INTRODUCTION: Controlled drug delivery systems can include the maintenance of drug levels within a desired range, the need for fewer administrations, optimal use of the drug in question, and increased patient compliance. higher cost of controlled-release systems compared with …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142099/
Sep 28, 2014 · The controlled drug delivery technology has progressed over the last six decades. It began in 1952 with the introduction of the first sustained release formulation. The 1st generation (1950-1980) of drug delivery was focused on developing oral and transdermal sustained release systems and establishing the controlled drug release mechanisms.Author: Kinam Park
https://pdfs.semanticscholar.org/2079/b751e16d7a9d34d2e0604a35a312d5bca4b2.pdf
According to the diffusion principle, controlled-release drug delivery systems can be designed as a reservoir system or a matrix system. Drugs released from both reservoir and matrix type devices follow the principle of diffusion, but they show two different release patterns as shown in Fig.
https://www.pharmatutor.org/articles/oral-controlled-release-drug-delivery-system-review
The basic rationale of a controlled release drug delivery system is to optimize the biopharmaceutics, pharmacokinetics, and pharmacodynamics properties of a drug in such a way that its utility is maximized through reduction in side effects and cure or control of disease condition in the shortest possible time by using smallest quantity of drug, administered by most suitable route.Author: M Gahlyan, S Jain
http://www.ijpacr.com/files/06-07-15/204072015.pdf
1.3 Oral Controlled Drug Delivery Systems Oral controlled release drug delivery is a system that provides continuous oral delivery of drugs at predictable and reproducible kinetics for a predetermined period throughout the course of GI transit and also the system that target the delivery of a drug …
https://www.hansvanlaarhoven.nl/reservoir-system/
Although controlled delivery from a monolithic device is very well possible, the presence of a membrane normally provides for a better release profile. In principle, a zero order release (constant release in time) can be approached with a reservoir system when the drug is dispersed in the core at a concentration that is far above the saturation ...
https://www.researchgate.net/publication/307671765_ORAL_CONTROLLED_RELEASE_DRUG_DELIVERY_SYSTEM_AN_OVERVIEW
Controlled release drug delivery system works on many different mechanisms to control the release rate of drugs. Various mechanisms like osmotic pressure, matrix system, reservoir system, altered density system etc. have been utilized as formulation approaches.
https://www.slideshare.net/suraj_mindgamer/factors-affecting-design-of-controlled-release-drug-delivery-systems
Sep 19, 2014 · Factors affecting design of Controlled Release Drug Delivery Systems Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. If you continue browsing the site, you agree to the use of cookies on this website.
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