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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142099/
Sep 28, 2014 · The controlled drug delivery technology has progressed over the last six decades. It began in 1952 with the introduction of the first sustained release formulation. The 1st generation (1950-1980) of drug delivery was focused on developing oral and transdermal sustained release systems and establishing the controlled drug release mechanisms.Author: Kinam Park
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are anticipated in the near future.
https://www.sciencedirect.com/topics/nursing-and-health-professions/drug-delivery-system
A drug delivery system (DDS) is defined as a formulation or a device that enables the introduction of a therapeutic substance into the body and improves its efficacy and safety by controlling the rate, time, and place of release of drugs in the body.
http://www.thepharmajournal.com/vol1Issue10/Issue_dec_2012/3.1.pdf
INTRODUCTION: Controlled drug delivery systems can include the maintenance of drug levels within a desired range, the need for fewer administrations, optimal use of the drug in question, and increased patient compliance. higher cost of controlled-release systems compared with …
https://www.crcpress.com/Controlled-Drug-Delivery-Systems/Opara/p/book/9780367187170
Discusses various controlled drug delivery systems, including sustained release delivery systems and pulse or delayed release, e.g. to target different regions of the gastrointestinal tract.
https://www.sciencedirect.com/science/article/pii/S0168365914002508
Controlled drug delivery technology has progressed over the last six decades. This progression began in 1952 with the introduction of the first sustained release formulation. The 1st generation of drug delivery (1950–1980) focused on developing oral and transdermal sustained release systems and establishing controlled drug release mechanisms.Author: Kinam Park
https://www.slideshare.net/ganapati123/controlled-drug-delivery-systems
Mar 18, 2013 · CONTROLLED DRUG DELIVERY SYSTEMS 1. 1 2. Controlled release• To achieve prolong therapeutic effect.• Implies predictability in drug release kinetics.• Deliver the drug at pre determined rate, locally or systematically. 2 3. Advantages• Improve patient convenience.• Reduction in fluctuation in steady state level.•
https://www.academia.edu/3339429/A_REVIEW_ON_ORAL_CONTROLLED_DRUG_DELIVERY
Recently, a new Controlled drug delivery occurs when a polymer generation of pharmaceutical products, called controlled is combined with a drug or active agent such that the release drug delivery systems, such as those developed release from the bulk material is pre-designed.
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