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https://insights.ovid.com/optometry-vision-science/opvis/1993/12/000/continuous-drug-delivery-use-disposable-contact/4/00006324
Disposable lenses soaked in pilocarpine hydrochloride or idoxuridine released drug for 30 min or less. These data indicate that disposable contact lenses could provide an acceptable means of drug delivery for some situations and overcome drawbacks associated with the use of nondisposable hydrogel lenses.Author: Gary A. Lesher, Gary G. Gunderson
https://www.eyehealthweb.com/drug-dispensing-contact-lenses/
The drug-delivery contact lenses have so far been tested only on an animal model. Before drug-delivering contact lenses can be made available on the market for eye doctors to prescribe, they must first go through rigorous clinical trials and be approved by the US Food and Drug Administration. It may be several years before these lenses are ...
https://www.sciencedirect.com/science/article/pii/S1367048407001038
Several methods have been proposed to make ophthalmic drugs deliverable by soft contact lens. In this review, the advantages and drawbacks of polymeric hydrogels for novel contact lens-based ophthalmic drug delivery systems are critically analyzed. 2. Polymeric hydrogels for conventional contact lens to absorb and release ophthalmic drugsAuthor: Li Xinming, Cui Yingde, Andrew W. Lloyd, Sergey V. Mikhalovsky, Susan R. Sandeman, Carol A. Howel, L...
https://www.ncbi.nlm.nih.gov/pubmed/15223815
Ophthalmic drug delivery through contact lenses. Gulsen D(1), Chauhan A. Author information: (1)University of Florida, Chemical Engineering Department, Gainesville, 32611, USA. PURPOSE: Currently available ophthalmic drug delivery systems are inefficient and may lead to side effects.Author: Derya Gulsen, Anuj Chauhan
https://www.sciencedirect.com/science/article/pii/S1773224714500214
Review of ophthalmic drug delivery by contact lenses K.-H. Hsu, S. Gause, A. Chauhan, â Ž [email protected] Department of Chemical Engineering, 1006 Center Drive, University of Florida, Gainesville, FL 32611, United States Department of Chemical Engineering, 1006 Center Drive University of Florida Gainesville FL 32611 United States * Correspondence Ophthalmic drugs are almost exclusively ...Author: K.-H. Hsu, S. Gause, A. Chauhan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039753/
Ocular drug delivery to the eyes through contact lenses has received much attention. Assuming the correlation of drug concentration at an intended site of action to pharmacological effects, drug delivery through contact lenses would provide a better control of drug concentration at the eyes 2,3.Author: Dasom Lee, Seungkwon Cho, Hwa Sung Park, Inchan Kwon
https://www.nature.com/articles/srep34194
Sep 28, 2016 · Ocular drug delivery through hydrogel contact lenses has great potential for the treatment of ocular diseases. Previous studies showed that the loading of lipophilic vitamin E to silicone-hydrogel ...Author: Dasom Lee, Seungkwon Cho, Hwa Sung Park, Inchan Kwon
https://link.springer.com/article/10.1007/s11095-008-9721-1
Sep 09, 2008 · The amorphous form of a drug may provide enhanced solubility, dissolution rate, and bioavailability but will also potentially crystallize over time. Miscible polymeric additives provide a means to increase physical stability. Understanding the miscibility of drug–polymer systems is of interest to optimize the formulation of such systems. The purpose of this work was to develop experimental ...Author: Patrick J. Marsac, Patrick J. Marsac, Tonglei Li, Lynne S. Taylor
https://onlinelibrary.wiley.com/doi/full/10.1111/cxo.12592
Contact lenses as a means to deliver pharmaceuticals to the eye have seen a significant increase in research interest in the past few years. This review will detail the in vitro experiments which have investigated use of these contact lenses in the context of the desired pharmacological treatment goals in the management of infectious, inflammatory, allergic and glaucomatous diseases of the eye.Author: Alex Hui
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