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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692765/
In addition to these methods, there are several other methods that are being developed for the delivery of siRNA in vivo, such as the direct siRNA conjugation method that utilizes the conjugation of the siRNA molecules to larger molecules like cholesterol (Wolfrum et al, 2007). However, the utility of this method for cancer therapy has not been ...Author: Christopher S. Gondi, Jasti S. Rao
https://onlinelibrary.wiley.com/doi/full/10.1002/jcp.21790
Muhammad Wahab Amjad, Prashant Kesharwani, Mohd Cairul Iqbal Mohd Amin and Arun K. Iyer, Recent advances in the design, development, and targeting mechanisms of polymeric micelles for delivery of siRNA in cancer therapy, Progress in Polymer Science, 10.1016/j.progpolymsci.2016.09.008, 64, (154-181), (2017).Author: Christopher S. Gondi, Jasti S. Rao
https://www.researchgate.net/publication/24356513_Concepts_in_In_Vivo_siRNA_Delivery_for_Cancer_Therapy
Advances have been made using siRNA as a delivery system for cancer therapy through local or targeted administration in vivo, 50 and the similarity between the miRNA and siRNA systems in silencing ...
https://onlinelibrary.wiley.com/doi/10.1002/jcp.21790
Concepts in in vivo siRNA delivery for cancer therapy. Christopher S. Gondi. Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine at Peoria, Peoria, Illinois. ... In vivo gene silencing using RNAi plays an important role in target validation and is advancing towards the development of RNAi‐based ...Author: Christopher S. Gondi, Jasti S. Rao
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009470/
In vivo miRNA delivery strategies for cancer therapy. A lot of work has been done in exploiting and evaluating the features of tumor and tumor microenvironment to improve RNA delivery. There are two classes of strategies for miRNA delivery — local and systemic delivery.Author: Yunching Chen, Dong Yu Gao, Leaf Huang
https://www.sciencedirect.com/science/article/pii/S0169409X14001033
Among various cancer treatments, miRNAs might represent a revolution in cancer therapy. 7. In vivo miRNA delivery strategies for cancer therapy. A lot of work has been done in exploiting and evaluating the features of tumor and tumor microenvironment to improve RNA delivery.Author: Yunching Chen, Dong Yu Gao, Leaf Huang
https://www.researchgate.net/publication/336161535_Rekindling_RNAi_Therapy_Materials_Design_Requirements_for_In_Vivo_siRNA_Delivery
The primary obstacle to realization of RNAi therapy has been the delivery of oligonucleotide payloads. ... for in vitro and in vivo siRNA delivery, and their knockdown ... are listed, and ordered ...
https://www.deepdyve.com/lp/wiley/concepts-in-in-vivo-sirna-delivery-for-cancer-therapy-SMpuwOK0WX
Aug 01, 2009 · Read "Concepts in in vivo siRNA delivery for cancer therapy, Journal of Cellular Physiology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
https://www.sciencedirect.com/science/article/pii/S1359644617304294
Especially in recent years, the nanocarrier-based delivery strategies have significantly promoted the application of siRNA in cancer therapy: (i) the siRNA therapeutics are efficiently protected after systematic administration and specifically delivered into the tumor cells for function; (ii) the biodistribution and pharmacokinetics of siRNAs ...Author: Penghui Zhang, Keli An, Xiaoman Duan, Hao Xu, Fei Li, Feng Xu
https://www.nature.com/articles/7700931
Jan 20, 2006 · The American Cancer Society estimates that, in 2005, a total of 1 372 910 new cancer cases and 570 280 deaths are expected in the United States. 1 These morbid statistics demonstrate the …Author: G R Devi
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