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https://www.researchgate.net/publication/272148044_Computational_Modeling_of_Nanoparticle_Targeted_Drug_Delivery
Computational Modeling of Nanoparticle Targeted Drug Delivery. Nanomedicine is a promising application of nanotechnology in medicine, which can drastically improve drug delivery efficiency through targeted delivery.
https://www.ingentaconnect.com/contentone/asp/rnn/2012/00000001/00000001/art00006
Mar 01, 2012 · This article discusses a few computational tools to model the nanoparticle delivery process and design nanoparticles for efficient targeted delivery. The modeling approaches span from continuum vascular flow, particle Brownian adhesion dynamics, to molecular level ligand-receptor binding. Computer simulation is envisioned to be able to optimize drug carrier design and predict drug delivery …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983427/
Numerous computational models have been developed to study the key steps in the nanomedicine pipeline, such as drug encapsulation and release [19,20], nanoparticle targeting, delivery and uptake [17,21–25], and nanoparticle effects on cells and tissues [26–27]. In particular, this article reviews recent progress in the development of computational models for a specific class of nanoparticle-based therapies: nanoparticle-mediated …Author: Chanchala D Kaddi, John H Phan, May D Wang
https://www.hindawi.com/journals/jnm/2016/1087250/
The aim of this paper is to review fabrication methods for the most common nanoparticle types (specifically self-assembly), targeted drug delivery processes, and the current state of NP computational modeling.Author: Xiaojiao Yu, Ian Trase, Muqing Ren, Kayla Duval, Xing Guo, Zi Chen
https://www.researchgate.net/profile/Jifu_Tan/publication/272148044_Computational_Modeling_of_Nanoparticle_Targeted_Drug_Delivery/links/57a0b40c08aeef35741b5574/Computational-Modeling-of-Nanoparticle-Targeted-Drug-Delivery.pdf
the targeted drug delivery by providing targeted selectiv-ity. Computational modeling tool will lead to insights of the dynamic delivery process, thus facilitate better design of nanoparticles.
https://www.sciencedirect.com/science/article/pii/S0168365919303244
Computational modeling used to predict cell kill as a function of drug release rates and binding affinities . (B) Endothelium-targeted nanoparticles (NPs) releasing their cargo in the intravascular space could be used to circumvent the poor diffusivity of NPs in the tumor interstitial space.Author: Milad Shamsi, Amir Mohammadi, Mohammad K.D. Manshadi, Amir Sanati-Nezhad
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956080/
Mar 01, 2014 · Introduction. Magnetic nanoparticles (MNPs) have been widely used in many bio-medicine applications such as drug delivery, drug releasing, and cancer diagnosis [1–5].It is a promising technique for curing diseases like cancer [], local injury [6,7], or local cell proliferation [].By applying an external magnetic field, the drug-carried MNPs can be targeted to the region of interest to avoid ...Author: Shunqiang Wang, Yihua Zhou, Jifu Tan, Jiang Xu, Jie Yang, Yaling Liu
http://europepmc.org/articles/PMC3956080
Mar 01, 2014 · Magnetic nanoparticles (MNPs) have been widely used in many bio-medicine applications such as drug delivery, drug releasing, and cancer diagnosis [1–5]. It is a promising technique for curing diseases like cancer , local injury [6,7], or local cell proliferation . By applying an external magnetic field, the drug-carried MNPs can be targeted to the region of interest to avoid full …
https://www.sciencedaily.com/releases/2015/10/151013155427.htm
Oct 13, 2015 · Computational models suggest new design for nanoparticles used in targeted drug delivery. FULL STORY. Using computational modeling, researchers at Carnegie Mellon University, the Colorado School of Mines and the University of California, …
https://www.entegris.com/content/en/home/resources/reference-materials/application-notes/appnote-drug-delivery-using-nanoparticles-10549.html
DRUG DELIVERY USING NANOPARTICLES — Considerable research and development is devoted to improving drug delivery through the use of nanoparticles. Although the definition of nanoparticle has become murky, typically they are defined being in the size range of 100 nm and below, Dynamic light scattering (DLS) is the preferred method in this size ...
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