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https://www.jgtps.com/admin/uploads/2OLVjN.pdf
Of the different approaches the new approaches like pressure controlled, osmotic controlled drug delivery systems are highly effective. Keywords: colon targeted drug delivery, prodrug, osmotic pressure, microflora, pH sensitivity, time dependence, nanoparticles, etc.File Size: 961KB
https://www.researchgate.net/publication/244994822_Colon_targeted_drug_delivery_systems-A_review
Colonic drug delivery has gained increased importance not just for the delivery of the drugs for the treatment of local diseases associated with the colon like Crohn's disease, ulcerative colitis, etc. but also for the systemic delivery of proteins, therapeutic peptides, anti-asthmatic drugs,...
https://sites.ualberta.ca/~csps/JPPS6(1)/S.Chourasia/colon.pdf
Bacteria of the lower GIT, however, secrete β-glucuronidase and can deglucuronidate a variety of drugs in the intestine (32). Since the deglucuronidation process results in the release of active drug and enables its reabsorption, glucuronide prodrugs would be expected to be superior for colon targeted drug delivery.
https://pharmawiki.in/colon-targeting-colonic-drug-delivery-uses-pharmacology-study-material-project-thesis-title/
Nov 21, 2017 · But now it is accepted as important site for drug delivery. DOWNLOAD PDF pharmacology notes. Colon targeting – Colonic drug delivery Uses Pharmacology Study Material – Project Thesis Title Pdf doc Colon targeting – Colonic drug delivery Uses Pharmacology Study Material – Project Thesis Title. Colon targeting is used to treat:-
http://www.ijpda.com/admin/uploads/QYr2wS.pdf
formulation of colon targeted drug delivery sys-tems such as Chitosan, Pectin, Chondroitin sul-phate, Cyclodextrins, Dextran, Guar gum, Inulin, Amylose and Locust bean gum [3]. Various drug delivery systems have been de-signed that deliver the drug quantitatively to the colon and then trigger the release of drug. Dif-
https://ijpsr.com/bft-article/colon-targeted-drug-delivery-system-a-review/?view=fulltext
Targeted drug delivery into the colon is highly desirable for local treatment of variety of bowl diseases such as ulcerative colitis, cirrhosis disease, amoebiasis, colonic cancer, local treatment of colonic pathologies and systemic delivery of protein and peptide drugs. The colon specific drug delivery system (CDDS) should be capable of ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215502/
Feb 07, 2010 · b. Novel Colon Targeted Delivery System (CODESTM) CODESTM is an unique CDDS technology that was designed to avoid the inherent problems associated with pH or time dependent systems.66, 67 CODESTM is a combined approach of pH dependent and microbially triggered CDDS.Author: Anil K. Philip, Betty Philip
http://www.thepharmajournal.com/archives/2012/vol1issue9/PartA/b.12.1.pdf
However, treatment can be made effective if the drugs can be targeted directly into the colon, thereby reducing the systemic side effects. General approaches for colon targeting drug delivery include use of prodrugs, pH dependent system, time dependent system and clonic microflora activated systems.Author: Malik K, Goswami L, Kothiyal P, Mukhopadhyay S
http://www.thepharmajournal.com/vol1Issue7/Issue_sept_2012/3.3.pdf
Colon targeted drug delivery system (CTDDS) delivered as both local and systemic delivery of drugs. Local delivery could, for example, allow topical treatment of inflammatory bowel disease (IBD). Treatment could be enhanced when drug delivered to the target site on the colon. Systemic side effects could also be reduced.
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