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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628713/
In the present paper, we used cationic liposomes for co-delivery of two types of siRNA and an anticancer drug into cancer cells. A liposomal delivery system was chosen because of its simplicity and high efficiency for the in vitro delivery of both the water-soluble drug and siRNA. This work was designed as a proof-of-concept study, in which we ...Author: Maha Saad, Olga B Garbuzenko, Tamara Minko
https://link.springer.com/article/10.1007/s41061-017-0113-z
Feb 07, 2017 · Recently, co-delivery of siRNA and anticancer drugs has drawn much attention in the treatment of drug-resistant cancers. Drug resistance is exhibited by cancer cells, which limits the efficacy of chemotherapy. When siRNA and anticancer drugs are delivered into cancer cells simultaneously, the siRNA is expected to silence the genes related to drug resistance, decreasing the drug efflux pumps ...Author: Haotian Sun, Iven Yarovoy, Meghan Capeling, Chong Cheng
https://www.sciencedirect.com/science/article/pii/S1369702114001849
This article provides a brief review on the recent developments of nanotechnology-based anticancer drug and/or siRNA delivery systems for cancer therapy. Particularly, the synergistic effects of combinatorial anticancer drug and siRNA therapy in various cancer models employing multifunctional drug/siRNA co-delivery nanocarriers have been discussed.Author: Manju Saraswathy, Shaoqin Gong
https://www.sciencedirect.com/science/article/pii/S0142961213015913
It is clear that the single treatment by either anticancer drug or siRNA delivered by LDH nanoparticles can only achieve limited success in cancer treatment, while the co-delivery of anticancer drugs and siRNA that are elegantly combined with LDH nanoparticles would synergistically enhance the efficacy in cancer treatment.Author: Li Li, Wenyi Gu, Jiezhong Chen, Jiezhong Chen, Weiyu Chen, Zhi P. Xu
https://www.researchgate.net/publication/23489414_Co-delivery_of_siRNA_and_an_anticancer_drug_for_treatment_of_multidrug-resistant_cancer
Co-delivery of siRNA and an anticancer drug for treatment of multidrug-resistant cancer Article in Nanomedicine 3(6):761-76 · January 2009 with 105 Reads How we measure 'reads'
https://www.medscape.com/viewarticle/585458_5
Oct 12, 2019 · A simultaneous co-delivery of DOX as a cell-death inducer/anticancer agent with siRNA targeted to MRP1 mRNA as a suppressor of drug-efflux pumps (pump resistance) and siRNA …
https://www.medscape.com/viewarticle/585458
Jan 14, 2009 · Cite this: Co-delivery of siRNA and an Anticancer Drug for Treatment of Multidrug-resistant Cancer - Medscape - Dec 01, 2008. References Authors and Disclosures
https://www.ncbi.nlm.nih.gov/pubmed/28176270
Polymers in the Co-delivery of siRNA and Anticancer Drugs for the Treatment of Drug-resistant Cancers. Sun H(1), Yarovoy I(1), Capeling M(1), Cheng C(2). Author information: (1)Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260, USA.Author: Haotian Sun, Iven Yarovoy, Meghan Capeling, Chong Cheng
https://www.researchgate.net/publication/313443463_Polymers_in_the_Co-delivery_of_siRNA_and_Anticancer_Drugs_for_the_Treatment_of_Drug-resistant_Cancers
Recently, co-delivery of siRNA and anticancer drugs has drawn much attention in the treatment of drug-resistant cancers. Drug resistance is exhibited by cancer cells, which limits the efficacy of ...
https://europepmc.org/articles/PMC2628713
Dec 01, 2008 · To develop a novel nanomedicine approach for the treatment of multidrug-resistant (MDR) cancer by combining an anticancer drug and suppressors of cellular resistance within one multifunctional nanocarrier-based delivery system (NDS).The NDS consisted of cationic liposomes (carrier, 100-140 nm), doxorubicin (DOX, anticancer drug), siRNA targeted to MRP1 and BCL2 …Author: Maha Saad, Olga B Garbuzenko, Tamara Minko
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