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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709991/
Apr 30, 2009 · Our results demonstrate that the AAV1/2 hybrid vector is an efficient CNS gene delivery method especially for the expression of a chemokine mutant in the brain due to its high expression level, long-term expression, negligible leak to blood, and minimal inflammatory response after brain parenchymal injection.Author: Tomomi Kiyota, Masaru Yamamoto, Bryce Schroder, Michael T. Jacobsen, Russell J. Swan, Mary P. Lamber...
https://www.hindawi.com/journals/bmri/2014/869269/
Present review highlights various drug delivery systems used for delivery of pharmaceutical agents mainly antibiotics, antineoplastic agents, neuropeptides, and other therapeutic substances through the endothelial capillaries (BBB) for CNS therapeutics. In addition, the use of ultrasound in delivery of therapeutic agents/biomolecules such as proline rich peptides, prodrugs ...Author: Ravi Kant Upadhyay
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627589/
Jun 25, 2019 · Drug delivery to the central nervous system (CNS) conferred by brain barriers is a major obstacle in the development of effective neurotherapeutics. In this review, a classification of current approaches of clinical or investigational importance for the delivery of …Author: Rana Abdul Razzak, Gordon John Florence, Francis James Gunn-Moore
https://www.drugtimes.org/formulation-design/noninvasive-cns-drug-delivery.html
A prodrug approach was used to enhance CNS delivery of the antiviral medications 2',3'-dideoxyinosine (ddI) and nelfinavir. In addition, inhibition of P-gp efflux was initiated to further increase the CNS delivery of the medications.
https://www.cnshealthcare.org/
We are a private non-profit human services agency that provides comprehensive behavioral health services. CNS Healthcare is a certified community behavioral health clinic (CCBHC) and offers a wide spectrum of community-based support services, psychiatry, medication management, psychotherapy, nursing services, and case management.
https://drug-dev.com/cns-delivery-bypassing-the-bbb-drug-delivery-from-the-olfactory-mucosa-to-the-cns/
T.R. Shantha, MD, PhD, FACA, explores and explains how therapeutic and non- therapeutic agents can reach the brain, bypassing through the formidable BBB based on the unique microanatomic and physiologic characteristics of the nasal olfactory mucosal route and its CNS connections that allow transportation directly into the CNS.
https://www.facebook.com/CNSExpressDelivery
CNS Express Delivery. 74 likes. "Anytime, Anywhere...consider it done!" Jump to. Sections of this page. Accessibility Help. Press alt + / to open this menu. Facebook. Email or Phone: ... Below is a summary of your request and our response. If this issue is not resolved to your satisfaction, you may reopen it within the next 7 days. Thank you ...3.7/5(2)
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