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https://www.ncbi.nlm.nih.gov/pubmed/28000386
Lower PEO content blends produced smaller diameter fibers with significantly faster insulin release kinetics. Insulin showed no reduction in bioactivity due to electrospinning. Buccal permeation of insulin facilitated by high chitosan content blends was significantly higher than that of free insulin.Author: Michael G. Lancina, Roopa Kanakatti Shankar, Hu Yang
https://www.sciencedirect.com/science/article/pii/S0939641112001038
Within the past 20 years, a considerable amount of work has been published on chitosan and its potential use in drug delivery systems. In contrast to all other polysaccharides having a monograph in a pharmacopeia, chitosan has a cationic character because of its primary amino groups.Author: Andreas Bernkop-Schnürch, Sarah Dünnhaupt
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534302/
This study aimed to prepare nanoemulsions coated with alginate/chitosan for oral insulin delivery. Uncoated nanoemulsions were prepared by homogenization of a water in oil in water (w/o/w) multiple emulsion that was composed of Labrafac ® CC, phospholipid, Span™ 80 and Cremorphor ® EL. Coating of the nanoemulsions was achieved based on polyelectrolyte cross-linking, with sequential ...Author: Xiaoyang Li, Jianping Qi, Yunchang Xie, Xi Zhang, Shunwen Hu, Ying Xu, Yi Lu, Wei Wu
https://www.degruyter.com/view/journals/jbcpp/31/2/article-20190147.xml?language=en
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https://link.springer.com/article/10.1007/s11095-007-9367-4
Jun 19, 2007 · To evaluate the pharmacological activity of insulin-loaded alginate/chitosan nanoparticles following oral dosage in diabetic rats. Nanoparticles were prepared by ionotropic pre-gelation of an alginate core followed by chitosan polyelectrolyte complexation. In vivo activity was evaluated by measuring the decrease in blood glucose concentrations in streptozotocin induced, …Author: B. Sarmento, A. Ribeiro, F. Veiga, P. Sampaio, R. Neufeld, D. Ferreira
https://www.webmd.com/vitamins/ai/ingredientmono-625/chitosan
Learn more about Chitosan uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Chitosan ... Robles-Cervantes JA. Chitosan improves insulin ...
https://www.researchgate.net/publication/6258833_AlginateChitosan_Nanoparticles_are_Effective_for_Oral_Insulin_Delivery
2201 Alginate/Chitosan Nanoparticles are Effective for Oral Insulin Delivery decrease of blood glucose levels was exclusively due to the physiologic effect of insulin.
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