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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751454/
Feb 05, 2008 · Chemical Drug Delivery Systems. A successful prodrug approach that utilizes improved lipophilicity and also requires a sequential bioactivation steps for conversion to an active drug and a brain tissue trapped intermediate is often referred in the literature as a chemical drug delivery system (CDS; 34–37). The CDS term was originally coined ...Author: Jarkko Rautio, Krista Laine, Mikko Gynther, Jouko Savolainen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407659/
Chemical modification such as prodrug targeting various nutrient transporters (amino acids, peptide and vitamin) has evolved a great deal ofintereSt to improve ocular drug delivery. In this review, we have discussed various prodrug strategies which have been widely applied for enhancing therapeutic efficacy of ophthalmic drugs.Author: Megha Barot, Mahuya Bagui, Mitan R. Gokulgandhi, Ashim K. Mitra
https://www.sciencedirect.com/science/article/pii/S131901641300042X
Retrometabolic drug design concept involves two approaches so as to improve the therapeutic index of drug candidates, chemical delivery system (CDS) and soft drug (SD) approach as shown in Fig. 2.Chemical delivery system is defined as one in which a biologically inert molecule is converted into an active drug by a number of steps enhancing the drug delivery at a particular organ or site (Bodor ...Author: Yashumati Ratan Bhardwaj, Ashutosh Pareek, Vivek Jain, Dharma Kishore
http://ajrconline.org/HTMLPaper.aspx?Journal=Asian%20Journal%20of%20Research%20in%20Chemistry;PID=2009-2-2-2
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https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/prodrugs
1.4.5.2 Prodrug(s) Prodrugs refer to the drug delivery system where the active constituent is being released after metabolism of the drug. Usually in prodrugs, the drug and a chemical moiety is covalently linked, although sometimes it characterizes the salt derivative of the active drug.
https://quizlet.com/59138147/drug-design-chapter-8-prodrugs-and-drug-delivery-systems-flash-cards/
Start studying Drug Design Chapter 8: Prodrugs and Drug Delivery Systems. Learn vocabulary, terms, and more with flashcards, games, and other study tools.
http://www.uobabylon.edu.iq/eprints/publication_12_14315_1587.pdf
Chemical Delivery Systems (Polymeric Prodrugs) ... A prodrug is a form of a drug that remains inactive during its delivery to the site of ... The possibility to form an advanced complex drug delivery system, which, in addition to drug and polymer carrier, may include several other …
https://www.mdpi.com/1420-3049/13/5/1035/htm
Among them, the chemical delivery system (CDS) approach is one of the most interesting procedures for delivering drugs in a sustained and specific manner to the CNS . It involves the release of active species from a lipophilic prodrug through a chemical and/or enzymatic multistep conversion.Author: Barbara Pavan, Alessandro Dalpiaz, Nunzia Ciliberti, Carla Biondi, Stefano Manfredini, Silvia Vertua...
https://www.researchgate.net/publication/236006801_Prodrug_Approach_to_Better_Drug_Delivery
The present article discusses about prodrug incorporated delivery system, ideal properties, limitation and targeting of prodrug.Introduction:The drug gives pharmacologic response by binding with ...
https://www.researchgate.net/publication/322930891_PRODRUGS_A_REVIEW
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