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https://www.sciencedirect.com/science/article/pii/S131901641300042X
Retrometabolic drug design concept involves two approaches so as to improve the therapeutic index of drug candidates, chemical delivery system (CDS) and soft drug (SD) approach as shown in Fig. 2.Chemical delivery system is defined as one in which a biologically inert molecule is converted into an active drug by a number of steps enhancing the drug delivery at a particular organ or site (Bodor ...Author: Yashumati Ratan Bhardwaj, Ashutosh Pareek, Vivek Jain, Dharma Kishore
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142369/
Retrometabolic drug design principle aims to design new, safe drugs with an improved therapeutic index and lesser side effects by integrating structure activity and structure metabolic relationships. Soft drug design and Chemical delivery system are the two approaches of retrometabolic drug design.Author: Yashumati Ratan Bhardwaj, Ashutosh Pareek, Vivek Jain, Dharma Kishore
https://www.researchgate.net/publication/319195506_Chitosan_and_its_Derivatives_as_Chemical_Drug_Delivery_Carriers
Method: This review is designed to afford an overview of CS and CS derivatives used as drug delivery carriers, with a special stress on chemical modifications of CS to attain specific biomedical ...
https://www.ncbi.nlm.nih.gov/pubmed/32083952
1. Drug Metab Rev. 2020 Feb;52(1):205-224. doi: 10.1080/03602532.2020.1726943. Epub 2020 Feb 21. Current trends in chemical modifications of magnetic nanoparticles for …
https://www.che.iitb.ac.in/research-area/drug-delivery
Unlike neutral polymers charged polymers (polyelectrolytes) such as DNA and proteins are promising nanomaterials for designing bioengineering platforms required for controlled drug delivery tissue engineering/cell attachment bio-conjugation etc. Synthetic polyelectrolytes have also been used for above-mentioned applications due to their ease of availability and low cost.
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