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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750274/
Characterization of 5-fluorouracil microspheres for colonic delivery 1. Heidelberger C, Chaudhuri NK, Danneburg P, et al. Fluorinated pyrimidine. 2. Langenbach RJ, Dancenberg PV, Heidelberger C. 3. Parker WB, Cheng YC. Metabolism and mechanism of action of 5 …Author: Ziyaur Rahman, Kanchan Kohli, Roop K. Khar, Mushir Ali, Naseem A. Charoo, Areeg A. A. Shamsher
https://link.springer.com/article/10.1208%2Fpt070247
The purpose of this investigation was to prepare and evaluate the colon-specific microspheres of 5-fluorouracil for the treatment of colon cancer. Core mic The core microspheres were coated with Eudragit S-100 by the solvent evaporation technique to prevent drug …Author: Ziyaur Rahman, Kanchan Kohli, Roop K. Khar, Mushir Ali, Naseem A. Charoo, Areeg A. A. Shamsher
http://europepmc.org/articles/PMC2750274
Jun 01, 2006 · The purpose of this investigation was to prepare and evaluate the colon-specific microspheres of 5-fluorouracil for the treatment of colon cancer. Core microspheres of alginate were prepared by the modified emulsification method in liquid paraffin and by cross-linking with calcium chloride. The core microspheres were coated with Eudragit S-100 by the solvent evaporation …
https://www.academia.edu/12334836/Characterization_of_5-fluorouracil_microspheres_for_colonic_delivery
Characterization of 5-fluorouracil microspheres for colonic delivery
https://www.researchgate.net/publication/312453813_Characterization_of_5-fuorouracil_microspheres_for_colonic_delivery
The coated microspheres did neither release the drug in acidic pH of stomach (pH 1.2) nor in small intestinal pH between 5 to 6.8, and the release started at pH 7.4, indicting perfect colonic ...
https://www.academia.edu/14364674/Characterization_of_5-fluorouracil_microspheres_for_colonic_delivery
Characterization of 5-fluorouracil microspheres for colonic delivery
https://core.ac.uk/display/8332201
The purpose of this investigation was to prepare and evaluate the colon-specific microspheres of 5-fluorouracil for the treatment of colon cancer. Core microspheres of alginate were prepared by the modified emulsification method in liquid paraffin and by cross-linking with calcium chloride.
https://www.sciencedirect.com/science/article/pii/S0168365903001950
Therefore, this work aimed the development of an oral delivery system for 5-fluorouracil which allows the release of the anticancer drug locally in the colon in dependence of luminal pH. This may reduce the systemic toxicity which is mainly the limiting factor in the treatment of colon cancer and allows a local dose increase compared to existing treatment strategies.Author: Alf Lamprecht, Hiromitsu Yamamoto, Hirofumi Takeuchi, Yoshiaki Kawashima
https://iom3.tandfonline.com/doi/full/10.1080/09205063.2020.1743946
(2020). Preparation and characterization of PLGA-PEG-PLGA polymeric nanoparticles for co-delivery of 5-Fluorouracil and Chrysin. Journal of Biomaterials Science, Polymer Edition. Ahead of Print.
https://www.sciencedirect.com/science/article/pii/S2311300616301847
Pectin is a natural polymer suitable as a colon-specific drug delivery vehicle in the treatment of colorectal cancer and other colonic diseases. 40 5- FU citrus pectin nanoparticles (CPNs) were fabricated and coated with Eudragit S100 (E-CPNs) for targeted delivery of colon cancer.Author: Suriyakala Perumal Chandran, Suriyakala Perumal Chandran, Satheesh Babu Natarajan, Sowmiya Chandrase...
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