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https://www.sciencedirect.com/science/article/pii/S0304419X09000705
Recent years have seen a surge in interest in cell-penetrating peptides (CPP) as an efficient means for delivering therapeutic targets into cellular compartments. The cell membrane is impermeable to hydrophilic substances yet linking to CPP can facilitate delivery into cells.Author: Nicole A. Brooks, Nicole A. Brooks, Dodie S. Pouniotis, Choon-Kit Tang, Vasso Apostolopoulos, Geoffr...
https://www.future-science.com/doi/10.4155/tde-2019-0042
For example, the cationic CPP, penetratin, stimulated the uptake of an OVA peptide antigen through the skin , while TAT helped in the cross-mucosal vaginal delivery of a DNA vaccine . While cationic peptides have been the most popular CPPs used for vaccine delivery, amphiphilic CPPs, such as VP22 , Pep-1 and MPG , have also been used ...Author: Mariusz Skwarczynski, Istvan Toth
https://www.researchgate.net/publication/26839565_Cell-penetrating_peptides_Application_in_vaccine_delivery
The cell penetrating property of these peptides have been utilized to deliver antigenic peptide and proteins into any antigen presenting cell including DCs for the development of vaccine delivery ...
https://www.academia.edu/33237078/Cell-penetrating_peptides_Application_in_vaccine_delivery
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https://www.ncbi.nlm.nih.gov/pubmed/25142954
In order to address this natural barrier, cell-penetrating peptides (CPPs) have been developed to facilitate molecular cargos to enter cells. CPPs, generally short peptides with 5-30 amino acids, can be classified in to cationic, amphipathic and hydrophobic types according to physical-chemical properties.Author: Yuhong Jiang, Man Li, Zhirong Zhang, Tao Gong, Xun Sun
http://www.eurekaselect.com/169269/article
Cell-penetrating peptides (CPPs) are especially attractive component of antigen delivery systems as they have been widely used to enhance drug transport into the cells. Fusing or co-delivery of antigen with CPPs can enhance antigen uptake, processing and presentation by antigen presenting cells (APCs), which are the fundamental steps in initiating an immune response.Author: Jieru Yang, Yacheng Luo, Mohini Anjna Shibu, Istvan Toth, Mariusz Skwarczynskia
https://www.researchgate.net/publication/264939703_Cell-Penetrating_Peptides_as_Delivery_Enhancers_for_Vaccine
Cell-Penetrating Peptides as Delivery Enhancers for Vaccine ... MN-based vaccine application delivers vaccine directly into skin and this is known to be immunologically more relevant vaccination ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931626/
Mar 28, 2016 · Cell penetrating peptides (CPP) or membrane translocating peptides (MTP) are a group of cationic peptides that have the ability to enter into the cytoplasm of cells. CPP are able to deliver a number of antigens, including RNA, DNA, peptides, proteins, drugs and virus particles into cells.Author: Vasso Apostolopoulos
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783919/
Jan 30, 2016 · 3.1. Cell-Penetrating Peptides as Vectors for Intracellular Peptide and Protein Delivery. CPP-mediated delivery of peptides and proteins has been successfully applied to target cancer, where the tumor suppressor p53 is a prominent target, as mutations in the gene encoding for p53 is responsible for more than 50% of cancer incidents.Author: Mie Kristensen, Ditlev Birch, Hanne Mørck Nielsen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770098/
Feb 25, 2016 · Cell-penetrating peptides (CPPs) are short amino acids that have been widely used to deliver macromolecules such as proteins, peptides, DNA, or RNA, to control cellular behavior for therapeutic purposes. CPPs have been used to treat immunological diseases through the delivery of immune modulatory molecules in vivo.Author: Sangho Lim, Sangho Lim, Ja-Hyun Koo, Ja-Hyun Koo, Je-Min Choi, Je-Min Choi
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