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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691962/
Therefore, the aim of the present study was to develop a topical gel formulation of celecoxib suited for iontophoretic delivery and to investigate the effects of some iontophoretic parameters on the transport of drug through excised rat skin.
https://www.ncbi.nlm.nih.gov/pubmed/30772460
Apr 05, 2019 · 1. Int J Pharm. 2019 Apr 5;560:365-376. doi: 10.1016/j.ijpharm.2019.02.011. Epub 2019 Feb 14. Combination of microneedles and microemulsions to increase celecoxib topical delivery for potential application in chemoprevention of breast cancer.Author: Gabriela Mojeiko, Moacir de Brito, Giovanna C. Salata, Luciana B. Lopes
https://www.sciencedirect.com/science/article/pii/S0378517319301346
Apr 05, 2019 · Topical delivery to the breast skin can overcome these problems. To overcome the barrier function of the skin, represented mainly by its outermost layer, the first goal of this study was to develop and optimize microemulsions as topical delivery systems for celecoxib.Author: Gabriela Mojeiko, Moacir de Brito, Giovanna C. Salata, Luciana B. Lopes
https://www.researchgate.net/publication/7985922_Topical_delivery_of_celecoxib_using_microemulsion
The topical delivery of celecoxib has been studied using microemulsion as the vehicle for the treatment of UV B induced skin cancer. Pseudotemary phase diagrams were constructed at different oil ...
https://www.tandfonline.com/doi/abs/10.3109/10717544.2012.724472
Topical administration of celecoxib proved to be an effective mean of preventing skin cancer development and improving anticancer drugs effectiveness in skin tumors treatment. The aim of this study was the development of an effective topical formulation of celecoxib, able to promote drug skin delivery, providing its in depth penetration through ...
https://www.tandfonline.com/doi/abs/10.1080/01932691.2011.620874
Aug 08, 2002 · In the present research, the potential of topical microemulsion delivery of poorly aqueous soluble drug, that is, Celecoxib, was investigated. Microemulsions are regarded as highly biocompatible topical carrier systems for the delivery of several anti-inflammatory, local anesthetics, anti-infective drugs.Author: Pankaj Kumar Sharma, Amoop Kumar
https://www.sciencedirect.com/science/article/pii/S1773224717306512
Albeit, the lower aqueous solubility of celecoxib (4 mg/L) and presence of intact barrier function of stratum corneum can bring about limitation for its topical application . However, in contrast to oral delivery, topical route for delivery permits the bypassing of hepatic first pass metabolism and …Author: H.V. Gangadharappa, Sarat M. Chandra Prasad, Rudra Pratap Singh
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