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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066571/
Dec 15, 2010 · However, due to the fact that cationic liposomes can be inactivated in the presence of serum, are unstable upon storage, and exhibit some cytotoxicity both in vitro and in vivo, anionic liposomes have been studied as potential gene delivery vehicles [63–65].Author: Daniel A. Balazs, Wt. Godbey
https://www.researchgate.net/publication/7471375_Cationic_liposomes_for_gene_delivery
Cationic liposomes for gene delivery. ... Aspects related to new trends in the formulation of lipid-based gene delivery systems aiming at overcoming some of their limitations will be covered ...
https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/cationic-liposome
Cationic liposome is one of the most commonly used nonviral gene delivery vectors and it is widely used as a standard gene vector especially for in vitro transfection (Ozpolat et al., 2014). The low toxicity, low immunogenicity, high loading capacity, and easy preparation contributed to the wide application of cationic liposomes.
https://www.hindawi.com/journals/jdd/2011/326497/
Various anionic liposomes have been characterized for gene delivery in a small number of cell types including CHO cells and primary hippocampal neurons [8, 66, 68, 69].While such investigations are novel, overall knowledge regarding anionic lipofection is as yet limited due to a lack of extensive testing; DNA entrapment in anionic liposomes is still inefficient, and cytotoxicity data remain ...Author: Daniel A. Balazs, Wt. Godbey
https://www.sciencedirect.com/science/article/pii/S181808761300010X
In addition to DOPE, other neutral lipids, including N-lauroylsarcosine , have been reported to enhance the gene delivery efficiency of cationic liposomes. 2.3. Lipid composition. The lipid composition of liposomes can affect the structural properties of the cationic lipids and their transfection efficiency.Author: Gayong Shim, Mi-Gyeong Kim, Joo Yeon Park, Yu-Kyoung Oh
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944014/
Cationic polymeric liposomes (CPLs) were successfully prepared using a tumor-targeting EGF protein modification for the systemic delivery of the p53 gene in ovarian cancer. These functional CPL nanoparticles (NPs) can be used as effective gene delivery ...Author: Li Zuo, Fengchun Zhang, Yingchun Xu
https://www.researchgate.net/profile/Henrique_Faneca/publication/7471375_Cationic_liposomes_for_gene_delivery/links/549560650cf29b944823add3/Cationic-liposomes-for-gene-delivery.pdf
Cationic liposomes for gene delivery 4 Expert Opin. Drug Deliv. (2005) 2(2) can limit their application, as the stability of lipoplexes on stor-age or in biological fluids can be drastically affected.
https://www.nature.com/articles/s41417-019-0141-7
Nov 02, 2019 · Liposomes are one of the most widely investigated carriers for CRISPR/Cas9 delivery. The surface properties of liposomal carriers, including …Author: Shuai Zhen, Shuai Zhen, Xu Li, Xu Li
https://pubs.acs.org/doi/full/10.1021/acscentsci.9b01052
Gene vectors play a critical role in gene therapy. To achieve efficient transfection, we developed a novel nonvirus cationic liposome (Lipo-Par), which was bound covalently with the cationic polypeptide pardaxin (Par). Interestingly, the Lipo-Pars exhibited highly enhanced gene transfection efficiency in various cell lines compared to that of the non-Par-bonded liposomes (Lipo-Nons). As a ...Author: Xiaoling Yuan, Bing Qin, Hang Yin, Yingying Shi, Mengshi Jiang, Lihua Luo, Zhenyu Luo, Junlei Zhang,...
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