Carbon Nanotubes Sirna Delivery

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SiRNA delivery with functionalized carbon nanotubes.

    https://www.ncbi.nlm.nih.gov/pubmed/21320582
    Sep 20, 2011 · SiRNA delivery with functionalized carbon nanotubes. Varkouhi AK(1), Foillard S, Lammers T, Schiffelers RM, Doris E, Hennink WE, Storm G. Author information: (1)Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Sorbonnelaan 16, 3584 CA Utrecht, The Netherlands.Author: Amir Khashayar Varkouhi, Stéphanie Foillard, Twan Lammers, Twan Lammers, Raymond M. Schiffelers, Eri...

SiRNA delivery with functionalized carbon nanotubes ...

    https://www.sciencedirect.com/science/article/pii/S0378517311001256
    Sep 20, 2011 · Carbon nanotubes (CNTs) have been studied for drug, antigen and nucleic acid delivery both in vitro and in vivo. Due to their nano-needle structure, they are supposed to cross the plasma membrane and enter directly into the cytoplasm likely upon an endocytosis-independent mechanism without inducing cell death.Author: Amir Khashayar Varkouhi, Stéphanie Foillard, Twan Lammers, Twan Lammers, Raymond M. Schiffelers, Eri...

Carbon Nanotubes: Solution for the Therapeutic Delivery of ...

    https://www.mdpi.com/1996-1944/5/2/278/htm
    Carbon nanotubes have many unique physical and chemical properties that are being widely explored for potential applications in biomedicine especially as transporters of drugs, proteins, DNA and RNA into cells. Specifically, single-walled carbon nanotubes (SWCNT) have been shown to deliver siRNA …Author: D. Lynn Kirkpatrick, Michelle Weiss, Anton Naumov, Geoffrey Bartholomeusz, R. Bruce Weisman, Olga Gl...

Carbon Nanotubes: Solution for the Therapeutic Delivery of ...

    https://www.mdpi.com/1996-1944/5/2/278/pdf
    of drugs, proteins, DNA and RNA into cells. Specifically, single-walled carbon nanotubes (SWCNT) have been shown to deliver siRNA to tumors in vivo. The low toxicity, the excellent membrane penetration ability, the protection afforded against blood breakdown of the siRNA payload and the good biological activity seen in vivo suggests that SWCNTAuthor: D. Lynn Kirkpatrick, Michelle Weiss, Anton Naumov, Geoffrey Bartholomeusz, R. Bruce Weisman, Olga Gl...

SiRNA delivery with functionalized carbon nanotubes ...

    https://www.researchgate.net/publication/49835600_SiRNA_delivery_with_functionalized_carbon_nanotubes
    The conjugation of siRNA to functionalized carbon nanotubes (f-CNTs) significantly increases their delivery into cells due to CNT uptake through mechanisms other than endocytosis [10]. On the ...

Single-Walled Carbon Nanotubes Noncovalently ...

    https://pubs.acs.org/doi/abs/10.1021/bc500280q
    Modified carbon nanotubes (CNTs) have been shown to protect siRNA and facilitate its entry into cells. However, simple and efficient methods to functionalize CNTs are needed. Here, noncovalent functionalization of CNTs is performed and shown to effectively deliver siRNA to target cells.Author: King S. Siu, Xiufen Zheng, Yanling Liu, Yujuan Zhang, Xusheng Zhang, Di Chen, Ken Yuan, Elizabeth R....

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