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https://www.sciencedirect.com/science/article/pii/S0968089607008541
Cationic lipids 1a–p, with carbamate linkages between hydrocarbon chains and quaternary ammonium heads, were synthesized for liposome-mediated gene delivery, and the biological performance of …Author: Dongliang Liu, Weihong Qiao, Zongshi Li, Xiuyun Cui, Kun Li, Lihua Yu, Kelu Yan, Limin Zhu, Lvbo Che...
https://www.ncbi.nlm.nih.gov/pubmed/26895503
May 01, 2016 · After recrystallization, carbamate-linked cationic lipids with high purity (over 95%) were obtained. The structures of these lipids were proved by IR spectrum, HR-ESI-MS, HPLC, (1)H NMR and (13)C NMR. The liposomes were prepared by using these cationic lipids and neutral lipid DOPE.Author: Jia Shi, Jia Shi, Shijun Yu, Jie Zhu, Defu Zhi, Yinan Zhao, Shaohui Cui, Shubiao Zhang
https://www.researchgate.net/publication/5894334_Carbamate-linked_cationic_lipids_for_gene_delivery
Cationic lipids have been often used as one of the major components in making most promising non-viral gene delivery systems, whereas sodium cholate, a surfactant so-called edge activator has been ...
https://www.sciencedirect.com/science/article/pii/S0927776516300996
In summary, a series of carbamate-linked cationic lipids with the hydrophobic chains of different chain length or unsaturated degree was prepared for gene delivery, and IR spectrum, HR-ESI-MS, HPLC, 1 H NMR and 13 C NMR data were used to confirm their structures. These cationic lipids had shown good pDNA binding ability and relatively high ...Author: Jia Shi, Jia Shi, Shijun Yu, Jie Zhu, Defu Zhi, Yinan Zhao, Shaohui Cui, Shubiao Zhang
https://www.ncbi.nlm.nih.gov/pubmed/17950607
Jan 15, 2008 · Series of cationic lipids 1a-p, with variable length of hydrocarbon chains, alternative quaternary ammonium heads, carbamate linkages between hydrocarbon chains and quaternary ammonium heads, as well as different anion combined with them, were synthesized for liposome-mediated gene delivery.Author: Dongliang Liu, Weihong Qiao, Zongshi Li, Xiuyun Cui, Kun Li, Lihua Yu, Kelu Yan, Limin Zhu, Lvbo Che...
https://www.researchgate.net/publication/7863453_Synthesis_of_carbamate-linked_lipids_for_gene_delivery
Series of lipids 1a-d and 2a,b, with carbamate linkages between hydrocarbon chains and ammonium or tertiary amine head, which were pH sensitive, were synthesized for liposome-mediated gene delivery.
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