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https://www.sciencedirect.com/science/article/pii/S0165247817301761
Nanoparticles and targeted drug delivery in cancer therapy. ... The mechanisms of nanoparticle internalization in cancer cells. ... Accordingly, coadministration of statins with DOX-loaded LDL conjugated NPs enhanced drug delivery into the CNS and induced tumor growth arrest .Author: Behdokht Bahrami, Behdokht Bahrami, Mohammad Hojjat-Farsangi, Mohammad Hojjat-Farsangi, Hamed Mohamm...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302817/
Dec 18, 2018 · DDS may specifically deliver a high dose of the therapeutic agent to the cancer cells and employ a sustained drug release with the healthy cells. Compared with the non-specific delivery device, ligand-conjugated nanoparticles (NPs) may be the most prospective among various DDSs.Author: Shijie Xu, Fangbo Cui, Dafu Huang, Dinghu Zhang, Anqing Zhu, Xia Sun, Yiming Cao, Sheng Ding, Yao Wa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924259
Nov 26, 2019 · Development of Adamantane-Conjugated TLR7/8 Agonists for Supramolecular Delivery and Cancer Immunotherapy. ... The findings demonstrate the ability of strong nanoparticle-drug interactions to limit systemic toxicity of TLR agonists while simultaneously maintaining therapeutic ... Development and screening of adamantane conjugated TLR7/8 agonists.Author: Christopher B. Rodell, Maaz S. Ahmed, Christopher S. Garris, Mikael J. Pittet, Ralph Weissleder
https://www.youtube.com/watch?v=TDvhVSXxnjw
Mar 07, 2016 · Admiral McRaven addresses the University of Texas at Austin Class of 2014 - Duration: 19:27. The University of Texas at Austin Recommended for youAuthor: Nathan Costa
https://www.genengnews.com/news/conjugated-nanoparticles-improve-chemo-drug-delivery/
Nov 16, 2018 · Findings from the new study were published recently in Small through an article entitled “Quinic Acid‐Conjugated Nanoparticles Enhance Drug Delivery to Solid Tumors via Interactions with ...
https://clincancerres.aacrjournals.org/content/11/23/8230
Dec 01, 2005 · The pharmacokinetic disposition of liposomal and nanoparticle agents is dependent on the carrier and not the parent drug until the drug is released from the carrier ().Thus, the pharmacology and pharmacokinetics of these agents are complex and detailed studies must be done to evaluate the disposition of the encapsulated or conjugated form of the drug and the released active drug ().Author: William C. Zamboni
https://www.cancer.gov/nano/cancer-nanotechnology/benefits
This image shows magnetic iron nanoparticles that target cells with IGF-1R receptors, and are conjugated to a chemotherapy drug (dark blue). In the tumor stroma of a mouse model of pancreatic cancer, the nanoparticles delivered the chemotherapy to tumor-associated macrophages expressing IGF-1R (red) and CD68 (green).
https://www.cancer.gov/nano/cancer-nanotechnology/treatment
Research on nanotechnology cancer therapy extends beyond drug delivery into the creation of new therapeutics available only through use of nanomaterial properties. Although small compared to cells, nanoparticles are large enough to encapsulate many small molecule compounds, which can be …
https://www.sciencedirect.com/science/article/pii/B9780323328890000145
Chapter 14 - Gold Nanoparticles in Cancer Drug Delivery. Author links open overlay panel Parvathy R. Chandran Reny Thankam Thomas. ... Nanoparticle-conjugated drug molecules can bypass the P-gp transporters and can be directly endocytosed into the cancer cells and thus the intracellular concentration of drug will be high enough for their action .Author: Parvathy R. Chandran, Reny Thankam Thomas
https://www.researchgate.net/publication/331888969_Nanoparticles_and_target_Drug_delivery_for_cancer_treatment_A_Comprehensive_review
In addition to the drug delivery systems in cancer have many barriers such as immune clearance or hepatic, renal. Thus, to improve treatment and overcome these problems the nanoparticle-loaded ...
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