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https://drug-dev.com/buccal-delivery-dissolvable-film-format-evolves-to-buccal-drug-delivery-applications/
Scott D. Barnhart indicates the buccal and sublingual oral mucosa will continue to be an area of growing interest for drug delivery as researchers evaluate ways to improve bioavailability, patient compliance, and product lifecycle beyond tablet and injectable formats.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436075/
Investigations on the buccal drug delivery systems . Several buccal drug delivery devices have been developed at the laboratory scale by many researchers either for local or systemic actions. They are broadly classified into (i) Solid buccal adhesive dosage forms (ii) Semi-solid buccal adhesive dosage forms (iii) Liquid buccal adhesive dosage ...Author: P Chinna Reddy, Chaitanya K.S.C., Y Madhusudan Rao
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848967/
Nov 05, 2019 · A number of advances in drug formulation have been made in the area of sublingual and buccal drug delivery. This review will focus on the physiological aspects that influence buccal and sublingual drug delivery and the advances in nanoparticulate drug delivery approaches for sublingual and buccal administration.Author: Susan Hua
https://www.healthline.com/health/sublingual-and-buccal-medication-administration
Sublingual and buccal medication administration are ways to take certain oral drugs. Learn the differences, pros, cons, and considerations for each.Author: Tricia Kinman
https://www.sciencedirect.com/science/article/pii/S1740674905000235
In the past decades, different drug delivery systems intended for buccal administration have been developed. The various buccal dosage forms described in the literature are summarized in Table 1.The most common formulations are tablets and patches.Author: Silvia Rossi, Giuseppina Sandri, Carla M. Caramella
https://www.mdpi.com/journal/pharmaceutics/special_issues/Buccal_Delivery
Buccal delivery is an alternative route of administration for either local delivery to the oral cavity or systemic release. The buccal route offers many advantages over conventional routes of drug delivery with an improved bioavailability at smaller doses than oral formulations due to the avoidance of degradation in the gastrointestinal tract ...
https://sites.ualberta.ca/~csps/JPPS1(1)/A.Shojaei/buccalreview.htm
Other than the low flux associated with buccal mucosal delivery, a major limitation of the buccal route of administration is the lack of dosage form retention at the site of absorption. Consequently, bioadhesive polymers have extensively been employed in buccal drug delivery systems.
http://www.pharmtech.com/current-status-buccal-drug-delivery
May 01, 2008 · Buccal mucosa allows drug delivery for both local and systemic therapies. Local delivery to tissues of the oral cavity has a number of applications, including treatment of local conditions such as periodontal disease, bacterial and fungal infections, aphthous stomatitis and vesiculo bullous diseases.
https://www.sciencedirect.com/topics/chemistry/buccal
Buccal delivery systems include mouthwashes, sprays, chewing gums, bioadhesive tablets, gels, and patches. Transbuccal delivery devices can be easily applied and removed. However, drug therapy within the oral cavity is subjected to a rapid elimination of drug due to the flushing action of saliva, and may require repeated and frequent doses.
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