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https://www.researchgate.net/publication/277805434_Buccal_Bioadhesive_Drug_Delivery_System_An_Overview
Buccal drug delivery system is only responsible for administration of retentive dosage form (Mujoriya et al., 2011 ). It is advantageous over transdermal delivery due to increased permeation, i.e., 4-4000 times greater than transdermal delivery ( Patel et al., 2011 ). Lamotrigine, an antiepileptic drug (AED) of the phenyltriazine class,...Author: Kinesh Patel
http://ijpba.info/ijpba/index.php/ijpba/article/download/237/169/0
Bioadhesive drug delivery formulations were introduced in 1947 when gum tragacanth was mixed with dental adhesive powder to apply penicillin to the oral mucosa; this was eventually to become Orabase ® [1]. Recently, considerable attention has been focused on the development of alternative drug delivery systems for proteins and peptide drugs.
https://ijpsr.com/bft-article/an-overview-on-buccal-drug-delivery-system/?view=fulltext
Buccal drug delivery holds a great promise for systemic delivery of orally inefficient drugs as well as a feasible and attractive alternative for non-invasive delivery of potent peptide and protein drug molecules.
https://japer.in/storage/models/article/wNpf3chMfN15jmoxMAGlq9nP2e1ZbzPjRPHnmG9j83MqvOc9538I2jYaD2DA/mucoadhesive-buccal-drug-delivery-an-overview.pdf
The main aim of buccal drug delivery of the drug as potential therapeutic agent is there instability in acidic environment, extensive first pass metabolism and low bioavailability of drug results an inadequate oral absorption. The buccal mucosa is rich in blood supply and relatively permeable.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436075/
Evaluation of Buccal Delivery Systems . Buccal adhesive drug delivery devices are subjected to the routine evaluation tests such as weight variation, thickness variation, friability, hardness, content uniformity, in vitro dissolution for tablets; tensile strength, film endurance, hygroscopicity etc. for films and patches; viscosity, effect of aging etc. for gels and ointments.Author: P Chinna Reddy, Chaitanya K.S.C., Y Madhusudan Rao
https://www.imedpub.com/articles/a-comprehensive-review-on-buccal-drug-delivery-system.pdf
delivery of therapeutic agents for both local and systemic delivery as retentive dosage form because buccal drug delivery system prolong the residence time of dosage form at the site and thus contribute to improved and/or better therapeutic performance of the drug.
https://www.sciencedirect.com/science/article/pii/S0939641119303376
Sep 01, 2019 · It was the aim of this study to assess in vitro methods for the characterization of mucoadhesive hydrogels for their potential to predict the residenc…Author: Randi Angela Baus, Forouhe Zahir-Jouzdani, Forouhe Zahir-Jouzdani, Sarah Dünnhaupt, Fatemeh Atyabi, ...
https://www.researchgate.net/publication/221750117_Mucoadhesive_drug_delivery_system_An_overview
Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of ...
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