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https://drug-dev.com/buccal-delivery-dissolvable-film-format-evolves-to-buccal-drug-delivery-applications/
BUCCAL DELIVERY – Dissolvable Film Format Evolves to Buccal Drug Delivery Applications INTRODUCTION The permeability of mucous membranes provides a convenient route for the systemic delivery of new and existing therapeutic drugs.
https://www.pharmatutor.org/articles/buccal-drug-delivery-system
Buccal delivery is defined as drug administration through the mucosal membranes lining the cheeks (buccal mucosa). The main impediment to the use of many hydrophilic macromolecular drugs as potential therapeutic agents is their inadequate and erratic oral absorption.
https://www.pharma-iq.com/pre-clinical-discovery-and-development/columns/buccal-delivery-simple-physical-chemical
Buccal delivery can be used for both systemic and local effects. On the down side the relative small surface area of the oral mucosa, a limited amount of aqueous media to solubilise the dose before absorption and the significant loss of drug due to uncontrolled swallowing and salivary flow – this combined with high requirements for good organoleptic properties are the main limitations of buccal delivery.Author: René Holm
https://www.sciencedirect.com/science/article/pii/S1740674905000235
Innovative drug delivery systems, such as lipophylic gel, buccal spray and phospholipid vesicles have been recently proposed to deliver peptides via the buccal route. In particular, some authors proposed the use of cubic and lamellar liquid crystalline phases of glyceryl monooleate as buccal drug carrier for peptide drugs [ 36 ].Author: Silvia Rossi, Giuseppina Sandri, Carla M. Caramella
https://pharmaxchange.info/2011/07/buccal-drug-delivery-system/
Jul 12, 2011 · Buccal delivery is the administration of the drug via buccal mucosa (lining of the cheek) to the systemic circulation.
https://www.sciencedirect.com/science/article/abs/pii/S0168365914003861
Whereas oral, nasal and pulmonary vaccine delivery strategies have been described extensively, the sublingual and buccal routes have received considerably less attention. In this review, the characteristics of and approaches for sublingual and buccal vaccine delivery are described and compared with other mucosal vaccine delivery sites.Author: Heleen Kraan, Hilde Vrieling, Cecil Czerkinsky, Wim Jiskoot, Gideon Kersten, Jean-Pierre Amorij
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