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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150040/
Jul 11, 2000 · The delivery of bronchodilators with metered-dose inhaler (MDI) in mechanically ventilated patients has attracted considerable interest in recent years. This is because the use of the MDI has several advantages over the nebulizer, such as reduced cost, ease of administration, less personnel time, reliability of dosing and a lower risk of contamination.Author: Dimitris Georgopoulos, Eleni Mouloudi, Eumorfia Kondili, Maria Klimathianaki
https://www.scottishambulance.com/UserFiles/file/healthprofessionals/Improvised%20BiPAP%20bronchiolator.pdf
via the BiPAP circuit and was unable to remove the nasal mask. Instead, standard oxygen tubing was connected to a connector on the nasal mask (Figure 3) and oxygen delivered into the nasal mask at 2 litres per minute. SpO2 was observed whilst a solution to delivering effective bronchodilator therapy …
http://www.rcjournal.com/contents/03.04/03.04.0270.pdf
CONCLUSIONS: Delivered oxygen concentration during BiPAP is a complex interaction be-tween the leak port type, the site of oxygen injection, the ventilator settings, and the oxygen flow. Because of this, it is important to continuously measure arterial oxygen saturation via pulse oximetry
https://www.cuimc.columbia.edu/file/44614/download?token=wYc04gZ9
Several delivery modes of bronchodilators are available for patients on invasive mechanical ventilation. As each delivery mode is believed to be similarly effective, the following list is in order of preference based on the guiding principle of minimizing the use of aerosol generating procedures with the aim to minimize risk of transmission to HCW.
https://www.advocatehealth.com/covid-19-info/_assets/documents/3.31-using-v60-bipap-device-as-invasive-ventilator.pdf
V60 BIPAP in Invasive Ventilation Mode. V60 BiPAP in Invasive Ventilation Mode Created date: 03/27/2020 Created by: Adult Respiratory Care Version date: 03/31/2020 . If there is no access to an invasive mechanical ventilator, the use of the Respironics V60 device may be used in the Invasive mode.
https://respiratorytherapycave.blogspot.com/2013/02/how-to-give-treatment-to-patient-on.html
Further studies should investigate the effects of inhaled bronchodilators on patient outcome and methods to optimize delivery of inhaled bronchodilators during noninvasive ventilation. So while further research is needed, common sense should indicate a significant amount of the aerisolized medication would impact on the circuit, and this would be greater with longer circuits.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076803/
Oct 18, 2016 · Bronchodilators (β 2 -agonists and antimuscarinics) are the mainstay of pharmacologic therapy in patients with COPD, with long-acting agents recommended for patients with moderate to severe symptoms or those who are at a higher risk for COPD exacerbations.Author: Donald P Tashkin
http://rc.rcjournal.com/content/60/6/880
Jun 01, 2015 · Noninvasive ventilation (NIV) and high-flow nasal cannula (HFNC) are increasingly used for patients with acute respiratory failure. Some patients receiving these therapies might also benefit from inhaled drug delivery. Thus, it is attractive to combine aerosol therapy with NIV or HFNC.
http://www.breas.com/wp-content/uploads/2014/10/Aerosol-Therapy-During-Noninvasive-Ventilation-Overview-Resp-Care-2015.pdf
Aerosol Delivery During HFNC Approaches to Improve Aerosol Delivery During HFNC Summary of Aerosol Delivery During HFNC Conclusions Noninvasive ventilation (NIV) and high-flow nasal cannula (HFNC) are increasingly used for patients with acute respiratory failure. Some patients receiving these therapies might also benefit from inhaled drug delivery.File Size: 412KB
http://rc.rcjournal.com/content/suppl/2015/01/30/respcare.03208.DC1/RT_Adult_Protocol_abbreviated.pdf
D. Indications for bronchodilator therapy, bronchial hygiene, volume expansion, aerosol therapy, sleep hygiene and oxygen therapy/EtCO2 and SpO2 monitoring are evaluated. A modality (e.g. hand-held nebulizer, O2 via nasal cannula, etc.) is selected if indicated.
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