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https://www.sciencedirect.com/science/article/pii/S1359644617302404
In this review, we highlight recent progress in the development of nanotechnology-based drug delivery for bone treatment, based on its improved delivery efficiency and safety. We summarize the most commonly used nanomaterials for bone drug delivery. We then discuss the targeting strategies of these nanomaterials to the diseased sites of bone ...Author: Hao Cheng, Hao Cheng, Hao Cheng, Aditya Chawla, Aditya Chawla, Aditya Chawla, Yafeng Yang, Yafeng Ya...
https://www.sciencedirect.com/science/article/pii/S0142961217307640
The limitations of current treatments urge scientists to develop bone marrow targeted drug delivery systems intended for the treatment of diseased bone marrow, which can improve the efficacy of therapeutic agents and reduce their dose-limiting systemic side effects on healthy tissues.Author: Chao-Feng Mu, Jianliang Shen, Jianliang Shen, Jing Liang, Hang-Sheng Zheng, Yang Xiong, Ying-Hui Wei...
https://www.mdpi.com/journal/pharmaceutics/special_issues/Bone_Target_Drug_Delivery
However, due to pan-skeleton biodistribution of hydroxyapatite-targeted drug delivery systems, the development of delivery systems with enhanced specificity for druggable sites within the skeleton represents a great challenge in the field of controlled drug targeting and delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699134/
Jun 25, 2013 · Targeted delivery for preventing and treating cancer bone metastasis. Tumor metastasis is a major cause of cancer-related deaths, and the bone tissue is a major site for several cancers to metastasize.23 Particularly, bone is the only site of metastasis for prostate cancer, whereas approximately 70% of metastatic breast cancers metastasize to bone.23,24 Therefore, the treatment …Author: Wenyi Gu, Chengtie Wu, Jiezhong Chen, Yin Xiao
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076608/
Bone marrow targeted drug delivery systems appear to offer a promising strategy for advancing diagnostic, protective, and/or therapeutic medicine for the hematopoietic system. Liposome technology can provide a drug delivery system with high bone marrow targeting that is mediated by specific phagocytosis in bone marrow.Author: Keitaro Sou, Beth Goins, Babatunde O. Oyajobi, Bruno L. Travi, William T. Phillips
https://onlinelibrary.wiley.com/doi/pdf/10.1111/os.12238
Targeted therapy for osteosarcoma includes organ, cell and molecular biological targeting; of these, organ targeting is the most mature. Bone-targeted drug delivery systems are used to concentrate chemotherapeutic drugs in bone tis-sues, thus potentially resolving the problem of reaching the desired foci and minimizing the toxicity and adverseAuthor: Cheng‐jun Li, Xiao‐zhou Liu, Lei Zhang, Long‐bang Chen, Xin Shi, Su‐jia Wu, Jian‐ning Zhao
https://ryortho.com/breaking/targeted-bone-healing-drug-from-purdue/
Nanoparticle Drug Delivery in Dogs With Osteosarcoma Elizabeth Hofheinz, M.P.H., M.Ed. • Mon, August 1st, 2016 . Researchers from the University of Illinois (U. of I.) have gone beyond the traditional mouse model used when testing a bone cancer drug delivery system…they went to the dogs.
https://pubs.acs.org/doi/10.1021/bc034090j
Bone-Targeted Drug Delivery Systems. 2016,,, 207-225. DOI: 10.1201/9781315370118-10. Tae-Kyung Ryu, Rae-Hyoung Kang, Ki-Young Jeong, Dae-Ryong Jun, Jung-Min Koh, Doyun Kim, Soo Kyung Bae, Sung-Wook Choi. Bone-targeted delivery of nanodiamond-based drug carriers conjugated with alendronate for potential osteoporosis treatment.Author: Dong Wang, Scott C Miller, Monika Sima, Pavla Kopečková, Jindrich Kopecek
https://www.youtube.com/watch?v=m3BBWguO6hs
Jun 08, 2016 · Atlanthera develops bone targeted delivery concept for treatments of bone tumors especially; 12b80 molecule action description through vectorization of active pharmaceutical ingredients to bone.Author: ATLANTHERA COMPANY
https://www.researchgate.net/publication/316769996_Development_of_nanomaterials_for_bone-targeted_drug_delivery
This review emphasizes recent progress in materials science that allows reliable scaffolds to be synthesized for targeted drug delivery in bone regeneration, also with respect to past directions ...
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