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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312395/
Dec 31, 2014 · In drug delivery. Bolaamphiphiles have been employed in drug delivery to design vesicular systems, hydrogels, and micellar systems to name a few. Molecular parameters are the dictating factors determining the geometrical shape assumed by bolaamphiphiles like micelles, rods, tubes, fibers and so on.Author: Fariya M, Jain A, Dhawan, Shah S, Nagarsenker Ms
https://www.sciencedirect.com/science/article/pii/S0014305718307018
Nanoscale drug delivery systems devised from biocompatible and biodegradable molecules with functional groups which are readily amenable to external stimuli, have become a promising approach to circumvent the pitfalls associated with the hydrophobic drugs concomitant with the amplification of …Author: Suchita Prasad, Katharina Achazi, Boris Schade, Rainer Haag, Sunil K. Sharma
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885142/
Recently, a series of novel symmetric bolaamphiphiles that form stable vesicles with potential applications in targeted drug delivery have been described. 157 Based on systematic changes in the bolaamphiphile structure and the relationships to the performance of the vesicles, new bolaamphiphiles that may form improved vesicles for targeted drug ...Author: Anu Puri, Kristin Loomis, Brandon Smith, Jae-Ho Lee, Amichai Yavlovich, Eliahu Heldman, Robert Blume...
https://www.researchgate.net/publication/236063634_In_Silico_In_Vitro_and_In_Vivo_Studies_Indicate_the_Potential_Use_of_Bolaamphiphiles_for_Therapeutic_siRNAs_Delivery
In Silico, In Vitro, and In Vivo Studies Indicate the Potential Use of Bolaamphiphiles for Therapeutic siRNAs Delivery Article (PDF Available) in Molecular Therapy - Nucleic Acids 2(3):e80 ...
http://dl.begellhouse.com/journals/3667c4ae6e8fd136,7a0c3bee026fb778,313cd9ee34e9e406.html
We will further describe nanoparticles derived from a novel class of amphipathic lipids called bolaamphiphiles with unique lipid assembly features that have been recently examined as …
https://www.onlinelibrary.wiley.com/doi/abs/10.1002/ejlt.200900107
Jan 25, 2010 · This paper describes bolaamphiphile synthesis and characterization of the nano‐sized vesicles formed from the bolaamphiphiles with potential application for targeted drug delivery to the brain. The starting material for the synthesis is vernonia oil (or its fatty acids or methyl esters), which is a naturally epoxidized triacylglycerol ...Author: Sarina Grinberg, Noa Kipnis, Charles Linder, Victoria Kolot, Eliahu Heldman
https://www.researchgate.net/publication/283716267_Nanoparticle_as_a_Targeting_Drug_Delivery_System_to_Blood_Brain_Barrier_A_Review
Nanoparticle as a Targeting Drug Delivery System to Blood Brain Barrier: A Review ... (NP) as a Targeting Drug Delivery System to . Blood-Brain Barrier ... bolaamphiphiles and nanoparticles can be ...
https://pubs.acs.org/doi/abs/10.1021/cr030602b
Mar 12, 2004 · Unprecedented parallel packing of unsymmetrical bolaamphiphiles driven by π–π stacking of cinnamoyl groups. Soft Matter 2010, 6 (14) , 3282. DOI: 10.1039/c002541k. Sarina Grinberg, Noa Kipnis, Charles Linder, Victoria Kolot, Eliahu Heldman. Asymmetric bolaamphiphiles from vernonia oil designed for drug delivery.
https://www.mdpi.com/2079-4991/8/2/115/pdf
to form a bola-like structure for mitochondria-targeting drug delivery [30]. Furthermore, the pH sensitive group (imidazole) was also used to improve transfection performance of the bolaamphiphiles for siRNA delivery by facilitating endosomal escape through “proton sponge effect” [21,25].Author: Zheng Huang, Dong-Mei Zhao, Xuan Deng, Ji Zhang, Yi-Mei Zhang, Xiao-Qi Yu
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